Analysis of the Dose Drop at the Edge of the Target Area in Heavy Ion Radiotherapy

Background. The dose distribution of heavy ions at the edge of the target region will have a steep decay during radiotherapy, which can better protect the surrounding organs at risk. Objective. To analyze the dose decay gradient at the back edge of the target region during heavy ion radiotherapy. Me...

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Autores principales:	Xiaoyun Ma, Mengling Zhang, Wanbin Meng, Xiaoli Lu, Ziheng Wang, Yanshan Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Computer applications to medicine. Medical informatics R858-859.7
Acceso en línea:	https://doaj.org/article/4f380dfee43a45f88203116420381c58
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spelling	oai:doaj.org-article:4f380dfee43a45f88203116420381c582021-11-22T01:10:41ZAnalysis of the Dose Drop at the Edge of the Target Area in Heavy Ion Radiotherapy1748-671810.1155/2021/4440877https://doaj.org/article/4f380dfee43a45f88203116420381c582021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/4440877https://doaj.org/toc/1748-6718Background. The dose distribution of heavy ions at the edge of the target region will have a steep decay during radiotherapy, which can better protect the surrounding organs at risk. Objective. To analyze the dose decay gradient at the back edge of the target region during heavy ion radiotherapy. Methods. Treatment planning system (TPS) was employed to analyze the dose decay at the edge of the beam under different incident modes and multiple dose segmentation conditions during fixed beam irradiation. The dose decay data of each plan was collected based on the position where the rear edge of the beam began to fall rapidly. Uniform scanning mode was selected in heavy ion TPS. Dose decay curves under different beam setup modes were drawn and compared. Results. The dose decay data analysis showed that in the case of single beam irradiation, the posterior edge of the beam was 5 mm away, and the posterior dose could drop to about 20%. While irradiation in opposite direction, the posterior edge of the beam was 5 mm away, and the dose could drop to about 50%. In orthogonal irradiation of two beams, the posterior edge of the beam could drop to about 30-38% in a distance of 5 mm. Through the data analysis in the TPS, the sharpness of the dose at the back edge of the heavy ion beam is better than that at the lateral edge, but the generated X-ray contamination cannot be ignored. Conclusions. The effect of uneven CT value on the dose decay of heavy ion beam should also be considered in clinical treatment.Xiaoyun MaMengling ZhangWanbin MengXiaoli LuZiheng WangYanshan ZhangHindawi LimitedarticleComputer applications to medicine. Medical informaticsR858-859.7ENComputational and Mathematical Methods in Medicine, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Computer applications to medicine. Medical informatics R858-859.7
spellingShingle	Computer applications to medicine. Medical informatics R858-859.7 Xiaoyun Ma Mengling Zhang Wanbin Meng Xiaoli Lu Ziheng Wang Yanshan Zhang Analysis of the Dose Drop at the Edge of the Target Area in Heavy Ion Radiotherapy
description	Background. The dose distribution of heavy ions at the edge of the target region will have a steep decay during radiotherapy, which can better protect the surrounding organs at risk. Objective. To analyze the dose decay gradient at the back edge of the target region during heavy ion radiotherapy. Methods. Treatment planning system (TPS) was employed to analyze the dose decay at the edge of the beam under different incident modes and multiple dose segmentation conditions during fixed beam irradiation. The dose decay data of each plan was collected based on the position where the rear edge of the beam began to fall rapidly. Uniform scanning mode was selected in heavy ion TPS. Dose decay curves under different beam setup modes were drawn and compared. Results. The dose decay data analysis showed that in the case of single beam irradiation, the posterior edge of the beam was 5 mm away, and the posterior dose could drop to about 20%. While irradiation in opposite direction, the posterior edge of the beam was 5 mm away, and the dose could drop to about 50%. In orthogonal irradiation of two beams, the posterior edge of the beam could drop to about 30-38% in a distance of 5 mm. Through the data analysis in the TPS, the sharpness of the dose at the back edge of the heavy ion beam is better than that at the lateral edge, but the generated X-ray contamination cannot be ignored. Conclusions. The effect of uneven CT value on the dose decay of heavy ion beam should also be considered in clinical treatment.
format	article
author	Xiaoyun Ma Mengling Zhang Wanbin Meng Xiaoli Lu Ziheng Wang Yanshan Zhang
author_facet	Xiaoyun Ma Mengling Zhang Wanbin Meng Xiaoli Lu Ziheng Wang Yanshan Zhang
author_sort	Xiaoyun Ma
title	Analysis of the Dose Drop at the Edge of the Target Area in Heavy Ion Radiotherapy
title_short	Analysis of the Dose Drop at the Edge of the Target Area in Heavy Ion Radiotherapy
title_full	Analysis of the Dose Drop at the Edge of the Target Area in Heavy Ion Radiotherapy
title_fullStr	Analysis of the Dose Drop at the Edge of the Target Area in Heavy Ion Radiotherapy
title_full_unstemmed	Analysis of the Dose Drop at the Edge of the Target Area in Heavy Ion Radiotherapy
title_sort	analysis of the dose drop at the edge of the target area in heavy ion radiotherapy
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/4f380dfee43a45f88203116420381c58
work_keys_str_mv	AT xiaoyunma analysisofthedosedropattheedgeofthetargetareainheavyionradiotherapy AT menglingzhang analysisofthedosedropattheedgeofthetargetareainheavyionradiotherapy AT wanbinmeng analysisofthedosedropattheedgeofthetargetareainheavyionradiotherapy AT xiaolilu analysisofthedosedropattheedgeofthetargetareainheavyionradiotherapy AT zihengwang analysisofthedosedropattheedgeofthetargetareainheavyionradiotherapy AT yanshanzhang analysisofthedosedropattheedgeofthetargetareainheavyionradiotherapy
_version_	1718418338021900288

Analysis of the Dose Drop at the Edge of the Target Area in Heavy Ion Radiotherapy

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