Molecular signatures of aneuploidy-driven adaptive evolution

Aneuploidy (abnormal chromosome number) can enable rapid adaptation to stress conditions, but it also entails fitness costs from gene imbalance. Here, the authors experimentally evolve yeast while forcing maintenance of aneuploidy to identify the mechanisms that promote tolerance of aneuploidy.

Guardado en:

Detalles Bibliográficos
Autores principales:	Alaattin Kaya, Marco Mariotti, Alexander Tyshkovskiy, Xuming Zhou, Michelle L. Hulke, Siming Ma, Maxim V. Gerashchenko, Amnon Koren, Vadim N. Gladyshev
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4f3f99b49ed24244a72ed99940240c13
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:4f3f99b49ed24244a72ed99940240c13
record_format	dspace
spelling	oai:doaj.org-article:4f3f99b49ed24244a72ed99940240c132021-12-02T15:34:13ZMolecular signatures of aneuploidy-driven adaptive evolution10.1038/s41467-019-13669-22041-1723https://doaj.org/article/4f3f99b49ed24244a72ed99940240c132020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13669-2https://doaj.org/toc/2041-1723Aneuploidy (abnormal chromosome number) can enable rapid adaptation to stress conditions, but it also entails fitness costs from gene imbalance. Here, the authors experimentally evolve yeast while forcing maintenance of aneuploidy to identify the mechanisms that promote tolerance of aneuploidy.Alaattin KayaMarco MariottiAlexander TyshkovskiyXuming ZhouMichelle L. HulkeSiming MaMaxim V. GerashchenkoAmnon KorenVadim N. GladyshevNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alaattin Kaya Marco Mariotti Alexander Tyshkovskiy Xuming Zhou Michelle L. Hulke Siming Ma Maxim V. Gerashchenko Amnon Koren Vadim N. Gladyshev Molecular signatures of aneuploidy-driven adaptive evolution
description	Aneuploidy (abnormal chromosome number) can enable rapid adaptation to stress conditions, but it also entails fitness costs from gene imbalance. Here, the authors experimentally evolve yeast while forcing maintenance of aneuploidy to identify the mechanisms that promote tolerance of aneuploidy.
format	article
author	Alaattin Kaya Marco Mariotti Alexander Tyshkovskiy Xuming Zhou Michelle L. Hulke Siming Ma Maxim V. Gerashchenko Amnon Koren Vadim N. Gladyshev
author_facet	Alaattin Kaya Marco Mariotti Alexander Tyshkovskiy Xuming Zhou Michelle L. Hulke Siming Ma Maxim V. Gerashchenko Amnon Koren Vadim N. Gladyshev
author_sort	Alaattin Kaya
title	Molecular signatures of aneuploidy-driven adaptive evolution
title_short	Molecular signatures of aneuploidy-driven adaptive evolution
title_full	Molecular signatures of aneuploidy-driven adaptive evolution
title_fullStr	Molecular signatures of aneuploidy-driven adaptive evolution
title_full_unstemmed	Molecular signatures of aneuploidy-driven adaptive evolution
title_sort	molecular signatures of aneuploidy-driven adaptive evolution
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/4f3f99b49ed24244a72ed99940240c13
work_keys_str_mv	AT alaattinkaya molecularsignaturesofaneuploidydrivenadaptiveevolution AT marcomariotti molecularsignaturesofaneuploidydrivenadaptiveevolution AT alexandertyshkovskiy molecularsignaturesofaneuploidydrivenadaptiveevolution AT xumingzhou molecularsignaturesofaneuploidydrivenadaptiveevolution AT michellelhulke molecularsignaturesofaneuploidydrivenadaptiveevolution AT simingma molecularsignaturesofaneuploidydrivenadaptiveevolution AT maximvgerashchenko molecularsignaturesofaneuploidydrivenadaptiveevolution AT amnonkoren molecularsignaturesofaneuploidydrivenadaptiveevolution AT vadimngladyshev molecularsignaturesofaneuploidydrivenadaptiveevolution
_version_	1718386898399920128

Molecular signatures of aneuploidy-driven adaptive evolution

Ejemplares similares