The Unfolded Protein Response as a Guardian of the Secretory Pathway

The endoplasmic reticulum (ER) is the major site of membrane biogenesis in most eukaryotic cells. As the entry point to the secretory pathway, it handles more than 10,000 different secretory and membrane proteins. The insertion of proteins into the membrane, their folding, and ER exit are affected b...

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Détails bibliographiques
Auteurs principaux: Toni Radanović, Robert Ernst
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
UPR
ER
Accès en ligne:https://doaj.org/article/4f4a8d6da1f94fa4a6333320540fc284
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