The Unfolded Protein Response as a Guardian of the Secretory Pathway

The endoplasmic reticulum (ER) is the major site of membrane biogenesis in most eukaryotic cells. As the entry point to the secretory pathway, it handles more than 10,000 different secretory and membrane proteins. The insertion of proteins into the membrane, their folding, and ER exit are affected b...

Full description

Saved in:
Bibliographic Details
Main Authors: Toni Radanović, Robert Ernst
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
UPR
ER
Online Access:https://doaj.org/article/4f4a8d6da1f94fa4a6333320540fc284
Tags: Add Tag
No Tags, Be the first to tag this record!