Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids
The authors generate EMLOs (elongating multi-lineage organized gastruloids): organoids that self-organize to form compartments with characteristics of the central nervous system, peripheral nervous system, mesenchyme, and gut tube.
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Nature Portfolio
2021
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oai:doaj.org-article:4f4d82bf6cee49a1b942d6d53d37773b2021-12-02T16:51:19ZCo-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids10.1038/s41467-021-23294-72041-1723https://doaj.org/article/4f4d82bf6cee49a1b942d6d53d37773b2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23294-7https://doaj.org/toc/2041-1723The authors generate EMLOs (elongating multi-lineage organized gastruloids): organoids that self-organize to form compartments with characteristics of the central nervous system, peripheral nervous system, mesenchyme, and gut tube.Zachary T. OlmstedJanet L. PaluhNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021) |
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Science Q Zachary T. Olmsted Janet L. Paluh Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids |
description |
The authors generate EMLOs (elongating multi-lineage organized gastruloids): organoids that self-organize to form compartments with characteristics of the central nervous system, peripheral nervous system, mesenchyme, and gut tube. |
format |
article |
author |
Zachary T. Olmsted Janet L. Paluh |
author_facet |
Zachary T. Olmsted Janet L. Paluh |
author_sort |
Zachary T. Olmsted |
title |
Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids |
title_short |
Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids |
title_full |
Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids |
title_fullStr |
Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids |
title_full_unstemmed |
Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids |
title_sort |
co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/4f4d82bf6cee49a1b942d6d53d37773b |
work_keys_str_mv |
AT zacharytolmsted codevelopmentofcentralandperipheralneuronswithtrunkmesendoderminhumanelongatingmultilineageorganizedgastruloids AT janetlpaluh codevelopmentofcentralandperipheralneuronswithtrunkmesendoderminhumanelongatingmultilineageorganizedgastruloids |
_version_ |
1718382976115408896 |