Calcium calmodulin kinase II activity is required for cartilage homeostasis in osteoarthritis

Abstract WNT ligands can activate several signalling cascades of pivotal importance during development and regenerative processes. Their de-regulation has been associated with the onset of different diseases. Here we investigated the role of the WNT/Calcium Calmodulin Kinase II (CaMKII) pathway in o...

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Autores principales: Giovanna Nalesso, Anne-Sophie Thorup, Suzanne Elizabeth Eldridge, Anna De Palma, Amanpreet Kaur, Kiran Peddireddi, Kevin Blighe, Sharmila Rana, Bryony Stott, Tonia Louise Vincent, Bethan Lynne Thomas, Jessica Bertrand, Joanna Sherwood, Antonella Fioravanti, Costantino Pitzalis, Francesco Dell’Accio
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4f50238f6e9a41a8bd45f631bc8299e2
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