Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes

The cellular composition of previous engineered heart tissue is often heterogeneous. Here, the authors create chamber-specific human pluripotent stem cell-derived cardiomyocytes to form both ventricular and atrial cells before embedding in collagen-based matrix to form ring-shaped engineered heart t...

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Autores principales:	Idit Goldfracht, Stephanie Protze, Assad Shiti, Noga Setter, Amit Gruber, Naim Shaheen, Yulia Nartiss, Gordon Keller, Lior Gepstein
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4f5787cf0b7f4b91911fe4781075ae85
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spelling	oai:doaj.org-article:4f5787cf0b7f4b91911fe4781075ae852021-12-02T15:34:34ZGenerating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes10.1038/s41467-019-13868-x2041-1723https://doaj.org/article/4f5787cf0b7f4b91911fe4781075ae852020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13868-xhttps://doaj.org/toc/2041-1723The cellular composition of previous engineered heart tissue is often heterogeneous. Here, the authors create chamber-specific human pluripotent stem cell-derived cardiomyocytes to form both ventricular and atrial cells before embedding in collagen-based matrix to form ring-shaped engineered heart tissue.Idit GoldfrachtStephanie ProtzeAssad ShitiNoga SetterAmit GruberNaim ShaheenYulia NartissGordon KellerLior GepsteinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Idit Goldfracht Stephanie Protze Assad Shiti Noga Setter Amit Gruber Naim Shaheen Yulia Nartiss Gordon Keller Lior Gepstein Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes
description	The cellular composition of previous engineered heart tissue is often heterogeneous. Here, the authors create chamber-specific human pluripotent stem cell-derived cardiomyocytes to form both ventricular and atrial cells before embedding in collagen-based matrix to form ring-shaped engineered heart tissue.
format	article
author	Idit Goldfracht Stephanie Protze Assad Shiti Noga Setter Amit Gruber Naim Shaheen Yulia Nartiss Gordon Keller Lior Gepstein
author_facet	Idit Goldfracht Stephanie Protze Assad Shiti Noga Setter Amit Gruber Naim Shaheen Yulia Nartiss Gordon Keller Lior Gepstein
author_sort	Idit Goldfracht
title	Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes
title_short	Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes
title_full	Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes
title_fullStr	Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes
title_full_unstemmed	Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes
title_sort	generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/4f5787cf0b7f4b91911fe4781075ae85
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Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes

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