How thioredoxin dissociates its mixed disulfide.

The dissociation mechanism of the thioredoxin (Trx) mixed disulfide complexes is unknown and has been debated for more than twenty years. Specifically, opposing arguments for the activation of the nucleophilic cysteine as a thiolate during the dissociation of the complex have been put forward. As a...

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Bibliographic Details
Main Authors: Goedele Roos, Nicolas Foloppe, Koen Van Laer, Lode Wyns, Lennart Nilsson, Paul Geerlings, Joris Messens
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
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Online Access:https://doaj.org/article/4f596919d83a42cda0c68aaf17e2fe37
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