Reducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk Ugandans: A protocol for a randomized controlled trial.

<h4>Introduction</h4>Stroke burden is rapidly increasing globally. Modifiable risk factors offer an opportunity to intervene, and targeting hypertension is a key actionable target for stroke risk reduction in sub-Saharan Africa. This 3-site planned randomized controlled trial builds on p...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mark Kaddumukasa, Josephine Najjuma, Scovia Nalugo Mbalinda, Martin N Kaddumukasa, Jane Nakibuuka, Christopher Burant, Shirley Moore, Carol Blixen, Elly T Katabira, Martha Sajatovic
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4f5d35bf67f64cb5b01db40476f53c84
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:4f5d35bf67f64cb5b01db40476f53c84
record_format	dspace
spelling	oai:doaj.org-article:4f5d35bf67f64cb5b01db40476f53c842021-12-02T20:03:51ZReducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk Ugandans: A protocol for a randomized controlled trial.1932-620310.1371/journal.pone.0251662https://doaj.org/article/4f5d35bf67f64cb5b01db40476f53c842021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0251662https://doaj.org/toc/1932-6203<h4>Introduction</h4>Stroke burden is rapidly increasing globally. Modifiable risk factors offer an opportunity to intervene, and targeting hypertension is a key actionable target for stroke risk reduction in sub-Saharan Africa. This 3-site planned randomized controlled trial builds on promising preliminary data.<h4>Methods</h4>A total of 246 Ugandan adults will be recruited randomized to experimental intervention vs. enhanced treatment control. Intervention participants will receive six weekly group-format stroke risk reduction self-management training sessions, and the controls will receive information on cardiovascular risk. The primary study outcome is systolic B.P. measured at baseline, 13-week, 24 weeks (6 months). Secondary outcomes include other biological and behavioral stroke risk factors.<h4>Discussion</h4>The curriculum-guided self-management TargetEd MAnageMent Intervention (TEAM) program is anticipated to reduce the stroke burden in Uganda.<h4>Trial registration</h4>ClinicalTrials.gov identifier: NCT04685408, registered on 28 December 2020.Mark KaddumukasaJosephine NajjumaScovia Nalugo MbalindaMartin N KaddumukasaJane NakibuukaChristopher BurantShirley MooreCarol BlixenElly T KatabiraMartha SajatovicPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0251662 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mark Kaddumukasa Josephine Najjuma Scovia Nalugo Mbalinda Martin N Kaddumukasa Jane Nakibuuka Christopher Burant Shirley Moore Carol Blixen Elly T Katabira Martha Sajatovic Reducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk Ugandans: A protocol for a randomized controlled trial.
description	<h4>Introduction</h4>Stroke burden is rapidly increasing globally. Modifiable risk factors offer an opportunity to intervene, and targeting hypertension is a key actionable target for stroke risk reduction in sub-Saharan Africa. This 3-site planned randomized controlled trial builds on promising preliminary data.<h4>Methods</h4>A total of 246 Ugandan adults will be recruited randomized to experimental intervention vs. enhanced treatment control. Intervention participants will receive six weekly group-format stroke risk reduction self-management training sessions, and the controls will receive information on cardiovascular risk. The primary study outcome is systolic B.P. measured at baseline, 13-week, 24 weeks (6 months). Secondary outcomes include other biological and behavioral stroke risk factors.<h4>Discussion</h4>The curriculum-guided self-management TargetEd MAnageMent Intervention (TEAM) program is anticipated to reduce the stroke burden in Uganda.<h4>Trial registration</h4>ClinicalTrials.gov identifier: NCT04685408, registered on 28 December 2020.
format	article
author	Mark Kaddumukasa Josephine Najjuma Scovia Nalugo Mbalinda Martin N Kaddumukasa Jane Nakibuuka Christopher Burant Shirley Moore Carol Blixen Elly T Katabira Martha Sajatovic
author_facet	Mark Kaddumukasa Josephine Najjuma Scovia Nalugo Mbalinda Martin N Kaddumukasa Jane Nakibuuka Christopher Burant Shirley Moore Carol Blixen Elly T Katabira Martha Sajatovic
author_sort	Mark Kaddumukasa
title	Reducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk Ugandans: A protocol for a randomized controlled trial.
title_short	Reducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk Ugandans: A protocol for a randomized controlled trial.
title_full	Reducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk Ugandans: A protocol for a randomized controlled trial.
title_fullStr	Reducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk Ugandans: A protocol for a randomized controlled trial.
title_full_unstemmed	Reducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk Ugandans: A protocol for a randomized controlled trial.
title_sort	reducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk ugandans: a protocol for a randomized controlled trial.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/4f5d35bf67f64cb5b01db40476f53c84
work_keys_str_mv	AT markkaddumukasa reducingstrokeburdenthroughatargetedselfmanagementinterventionforreducingstrokeriskfactorsinhighriskugandansaprotocolforarandomizedcontrolledtrial AT josephinenajjuma reducingstrokeburdenthroughatargetedselfmanagementinterventionforreducingstrokeriskfactorsinhighriskugandansaprotocolforarandomizedcontrolledtrial AT scovianalugombalinda reducingstrokeburdenthroughatargetedselfmanagementinterventionforreducingstrokeriskfactorsinhighriskugandansaprotocolforarandomizedcontrolledtrial AT martinnkaddumukasa reducingstrokeburdenthroughatargetedselfmanagementinterventionforreducingstrokeriskfactorsinhighriskugandansaprotocolforarandomizedcontrolledtrial AT janenakibuuka reducingstrokeburdenthroughatargetedselfmanagementinterventionforreducingstrokeriskfactorsinhighriskugandansaprotocolforarandomizedcontrolledtrial AT christopherburant reducingstrokeburdenthroughatargetedselfmanagementinterventionforreducingstrokeriskfactorsinhighriskugandansaprotocolforarandomizedcontrolledtrial AT shirleymoore reducingstrokeburdenthroughatargetedselfmanagementinterventionforreducingstrokeriskfactorsinhighriskugandansaprotocolforarandomizedcontrolledtrial AT carolblixen reducingstrokeburdenthroughatargetedselfmanagementinterventionforreducingstrokeriskfactorsinhighriskugandansaprotocolforarandomizedcontrolledtrial AT ellytkatabira reducingstrokeburdenthroughatargetedselfmanagementinterventionforreducingstrokeriskfactorsinhighriskugandansaprotocolforarandomizedcontrolledtrial AT marthasajatovic reducingstrokeburdenthroughatargetedselfmanagementinterventionforreducingstrokeriskfactorsinhighriskugandansaprotocolforarandomizedcontrolledtrial
_version_	1718375599886565376

Reducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk Ugandans: A protocol for a randomized controlled trial.

Ejemplares similares