Effects of milnacipran on binge eating – a pilot study
Shun’ichi Noma1, Teruhisa Uwatoko1, Haruka Yamamoto2, Takuji Hayashi11Department of Psychiatry, Graduate School of Medicine, Kyoto University, Kyoto, Japan; 2Department of Psychiatry, Toyooka Hospital, Hyogo, JapanAbstract: Selective serotonin reuptake inhibitors and selective norepine...
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Dove Medical Press
2008
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oai:doaj.org-article:4f60c24c4ad3406a994b44405138bc882021-12-02T01:11:40ZEffects of milnacipran on binge eating – a pilot study1176-63281178-2021https://doaj.org/article/4f60c24c4ad3406a994b44405138bc882008-03-01T00:00:00Zhttp://www.dovepress.com/effects-of-milnacipran-on-binge-eating-ndash-a-pilot-study-a1012https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Shun’ichi Noma1, Teruhisa Uwatoko1, Haruka Yamamoto2, Takuji Hayashi11Department of Psychiatry, Graduate School of Medicine, Kyoto University, Kyoto, Japan; 2Department of Psychiatry, Toyooka Hospital, Hyogo, JapanAbstract: Selective serotonin reuptake inhibitors and selective norepinephrine reuptake inhibitors are effective in the treatment of bulimia nervosa. There have been relatively few studies of the efficacy of specific serotonin and norepinephrine reuptake inhibitors in the treatment of eating disorders. Twenty-five outpatients with binge eating episodes, diagnosed as anorexia nervosa, binge-eating/purging type, bulimia nervosa/purging type, or bulimia nervosa/non-purging type, were treated with milnacipran and 20 patients completed the 8-week study. Symptom severity was evaluated using the Bulimic Investigatory Test, Edinburgh (BITE) self-rating scale before administration of milnacipran and after 1, 4, and 8 weeks treatment. The scores improved after 8 weeks, especially drive to, and regret for, binge eating. Milnacipran was more effective in patients without purging and in younger patients, while there was no difference in the efficacy of milnacipran among subtypes of eating disorders.Keywords: milnacipran, specific serotonin and norepinephrine reuptake inhibitors, binge eating, vomiting, eating disorder, pharmacotherapy Shun’ichi NomaTeruhisa UwatokoHaruka YamamotoTakuji HayashiDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2008, Iss Issue 1, Pp 295-300 (2008) |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Shun’ichi Noma Teruhisa Uwatoko Haruka Yamamoto Takuji Hayashi Effects of milnacipran on binge eating – a pilot study |
| description |
Shun’ichi Noma1, Teruhisa Uwatoko1, Haruka Yamamoto2, Takuji Hayashi11Department of Psychiatry, Graduate School of Medicine, Kyoto University, Kyoto, Japan; 2Department of Psychiatry, Toyooka Hospital, Hyogo, JapanAbstract: Selective serotonin reuptake inhibitors and selective norepinephrine reuptake inhibitors are effective in the treatment of bulimia nervosa. There have been relatively few studies of the efficacy of specific serotonin and norepinephrine reuptake inhibitors in the treatment of eating disorders. Twenty-five outpatients with binge eating episodes, diagnosed as anorexia nervosa, binge-eating/purging type, bulimia nervosa/purging type, or bulimia nervosa/non-purging type, were treated with milnacipran and 20 patients completed the 8-week study. Symptom severity was evaluated using the Bulimic Investigatory Test, Edinburgh (BITE) self-rating scale before administration of milnacipran and after 1, 4, and 8 weeks treatment. The scores improved after 8 weeks, especially drive to, and regret for, binge eating. Milnacipran was more effective in patients without purging and in younger patients, while there was no difference in the efficacy of milnacipran among subtypes of eating disorders.Keywords: milnacipran, specific serotonin and norepinephrine reuptake inhibitors, binge eating, vomiting, eating disorder, pharmacotherapy |
| format |
article |
| author |
Shun’ichi Noma Teruhisa Uwatoko Haruka Yamamoto Takuji Hayashi |
| author_facet |
Shun’ichi Noma Teruhisa Uwatoko Haruka Yamamoto Takuji Hayashi |
| author_sort |
Shun’ichi Noma |
| title |
Effects of milnacipran on binge eating – a pilot study |
| title_short |
Effects of milnacipran on binge eating – a pilot study |
| title_full |
Effects of milnacipran on binge eating – a pilot study |
| title_fullStr |
Effects of milnacipran on binge eating – a pilot study |
| title_full_unstemmed |
Effects of milnacipran on binge eating – a pilot study |
| title_sort |
effects of milnacipran on binge eating – a pilot study |
| publisher |
Dove Medical Press |
| publishDate |
2008 |
| url |
https://doaj.org/article/4f60c24c4ad3406a994b44405138bc88 |
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| _version_ |
1718403253417279488 |