Cell-free reconstitution reveals centriole cartwheel assembly mechanisms
The centriole is an organelle composed of rings of SAS-6 proteins that form a cartwheel structure. Here the authors develop a cell-free system to examine core cartwheel assembly ofC. reinhardtiiproteins and discover that CrSAS-6 has autonomous properties that facilitates self-organized stacking of p...
Enregistré dans:
Auteurs principaux: | P. Guichard, V. Hamel, M. Le Guennec, N. Banterle, I. Iacovache, V. Nemčíková, I. Flückiger, K. N. Goldie, H. Stahlberg, D. Lévy, B. Zuber, P. Gönczy |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/4f6600af449c44168ab5b99cf0a0b96c |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly
par: Georgios N. Hatzopoulos, et autres
Publié: (2021) -
Role of CAP350 in centriolar tubule stability and centriole assembly.
par: Mikael Le Clech
Publié: (2008) -
Over-elongation of centrioles in cancer promotes centriole amplification and chromosome missegregation
par: Gaëlle Marteil, et autres
Publié: (2018) -
Coping with centriole loss: pericentriolar material maintenance after centriole degeneration
par: Carla M. C. Abreu, et autres
Publié: (2021) -
Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly
par: Yi Liu, et autres
Publié: (2018)