Cell-free reconstitution reveals centriole cartwheel assembly mechanisms

Cell-free reconstitution reveals centriole cartwheel assembly mechanisms

The centriole is an organelle composed of rings of SAS-6 proteins that form a cartwheel structure. Here the authors develop a cell-free system to examine core cartwheel assembly ofC. reinhardtiiproteins and discover that CrSAS-6 has autonomous properties that facilitates self-organized stacking of p...

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Main Authors: P. Guichard, V. Hamel, M. Le Guennec, N. Banterle, I. Iacovache, V. Nemčíková, I. Flückiger, K. N. Goldie, H. Stahlberg, D. Lévy, B. Zuber, P. Gönczy
Format: article
Language:EN
Published: Nature Portfolio 2017
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Science
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Online Access:https://doaj.org/article/4f6600af449c44168ab5b99cf0a0b96c
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