Contribution of p53 in sensitivity to EGFR tyrosine kinase inhibitors in non-small cell lung cancer
Abstract The emergence of resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC) with activating EGFR mutations is a major hindrance to treatment. We investigated the effects of p53 in primary sensitivity and acquired resistance...
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Main Authors: | , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/4f71769b43da4ae2a10dadce8fbefd82 |
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