A <named-content content-type="genus-species">Trypanosoma brucei</named-content> ORFeome-Based Gain-of-Function Library Identifies Genes That Promote Survival during Melarsoprol Treatment

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A <named-content content-type="genus-species">Trypanosoma brucei</named-content> ORFeome-Based Gain-of-Function Library Identifies Genes That Promote Survival during Melarsoprol Treatment

ABSTRACT Trypanosoma brucei is an early branching protozoan parasite that causes human and animal African trypanosomiasis. Forward genetics approaches are powerful tools for uncovering novel aspects of trypanosomatid biology, pathogenesis, and therapeutic approaches against trypanosomiasis. Here, we...

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Détails bibliographiques
Auteurs principaux:	McKenzie Carter, Stephanie Gomez, Sam Gritz, Stephen Larson, Eugenia Silva-Herzog, Hee-Sook Kim, Danae Schulz, Galadriel Hovel-Miner
Format:	article
Langue:	EN
Publié:	American Society for Microbiology 2020
Sujets:	forward genetics ORFeome Trypanosoma drug resistance mechanisms parasitology redox signaling Microbiology QR1-502
Accès en ligne:	https://doaj.org/article/4f79edd8fc384cc39d232719ea2712d4
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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