A rapid and robust method for single cell chromatin accessibility profiling

ATAC-seq is widely used to identify regulatory regions in the genome. Here the authors develop a simple and robust plate-based single-cell ATAC-seq method that works in fresh and cryopreserved cells.

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Autores principales: Xi Chen, Ricardo J. Miragaia, Kedar Nath Natarajan, Sarah A. Teichmann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/4f8114e572994fd2b334a80d5dbcfc5c
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spelling oai:doaj.org-article:4f8114e572994fd2b334a80d5dbcfc5c2021-12-02T14:41:28ZA rapid and robust method for single cell chromatin accessibility profiling10.1038/s41467-018-07771-02041-1723https://doaj.org/article/4f8114e572994fd2b334a80d5dbcfc5c2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07771-0https://doaj.org/toc/2041-1723ATAC-seq is widely used to identify regulatory regions in the genome. Here the authors develop a simple and robust plate-based single-cell ATAC-seq method that works in fresh and cryopreserved cells.Xi ChenRicardo J. MiragaiaKedar Nath NatarajanSarah A. TeichmannNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xi Chen
Ricardo J. Miragaia
Kedar Nath Natarajan
Sarah A. Teichmann
A rapid and robust method for single cell chromatin accessibility profiling
description ATAC-seq is widely used to identify regulatory regions in the genome. Here the authors develop a simple and robust plate-based single-cell ATAC-seq method that works in fresh and cryopreserved cells.
format article
author Xi Chen
Ricardo J. Miragaia
Kedar Nath Natarajan
Sarah A. Teichmann
author_facet Xi Chen
Ricardo J. Miragaia
Kedar Nath Natarajan
Sarah A. Teichmann
author_sort Xi Chen
title A rapid and robust method for single cell chromatin accessibility profiling
title_short A rapid and robust method for single cell chromatin accessibility profiling
title_full A rapid and robust method for single cell chromatin accessibility profiling
title_fullStr A rapid and robust method for single cell chromatin accessibility profiling
title_full_unstemmed A rapid and robust method for single cell chromatin accessibility profiling
title_sort rapid and robust method for single cell chromatin accessibility profiling
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/4f8114e572994fd2b334a80d5dbcfc5c
work_keys_str_mv AT xichen arapidandrobustmethodforsinglecellchromatinaccessibilityprofiling
AT ricardojmiragaia arapidandrobustmethodforsinglecellchromatinaccessibilityprofiling
AT kedarnathnatarajan arapidandrobustmethodforsinglecellchromatinaccessibilityprofiling
AT sarahateichmann arapidandrobustmethodforsinglecellchromatinaccessibilityprofiling
AT xichen rapidandrobustmethodforsinglecellchromatinaccessibilityprofiling
AT ricardojmiragaia rapidandrobustmethodforsinglecellchromatinaccessibilityprofiling
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