Glucoherb versus metformin on glycemic markers and glycosylated hemoglobin in prediabetes patients; a clinical trial study

Introduction: There is a high risk of diabetes mellitus in pre-diabetic patients. Objectives: The aim of the study was to compare the effect of the extracts of these herbs in the formulation of Glucoherb supplementation versus metformin in pre-diabetes patients on glycemic markers and glycosylated h...

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Autores principales:	Iman Izadi, Rahil Riahi Samani, Afsaneh Malekpour Tehrani, Marziyeh Dehghani, Alireza Jafari
Formato:	article
Lenguaje:	EN
Publicado:	Society of Diabetic Nephropathy Prevention 2021
Materias:	glucoherb diabetes mellitus fasting blood sugar glycated hemoglobin metformin pre-diabetic Therapeutics. Pharmacology RM1-950 Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/4f81519ec97947639259be090a07edb1
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spelling	oai:doaj.org-article:4f81519ec97947639259be090a07edb12021-11-17T08:13:57ZGlucoherb versus metformin on glycemic markers and glycosylated hemoglobin in prediabetes patients; a clinical trial study2345-420210.34172/npj.2021.08https://doaj.org/article/4f81519ec97947639259be090a07edb12021-01-01T00:00:00Zhttps://jnephropharmacology.com/PDF/npj-10348https://doaj.org/toc/2345-4202Introduction: There is a high risk of diabetes mellitus in pre-diabetic patients. Objectives: The aim of the study was to compare the effect of the extracts of these herbs in the formulation of Glucoherb supplementation versus metformin in pre-diabetes patients on glycemic markers and glycosylated hemoglobin. Patients and Methods: Pre-diabetic patients who had indication of drug treatment according to the criteria of the American Diabetes Association, were selected and randomly divided into two groups of Glucoherb and metformin. Body mass index (BMI), fasting blood sugar (FBS), 2 hours postprandial blood glucose (BS2PP) and glycosylated hemoglobin (HbA1c) were measured before and after the intervention. Results: The mean BMI, FBS, BS2PP and HbA1c levels were significantly decreased after intervention in both Glucoherb and metformin groups (P < 0.05) without any significant difference between them (P < 0.05). Conclusion: Glucoherb showed similar efficacy to metformin in reducing blood glucose, BMI and HbA1c in pre-diabetic patients.Iman IzadiRahil Riahi SamaniAfsaneh Malekpour TehraniMarziyeh DehghaniAlireza JafariSociety of Diabetic Nephropathy Prevention articleglucoherbdiabetes mellitusfasting blood sugarglycated hemoglobinmetforminpre-diabeticTherapeutics. PharmacologyRM1-950Diseases of the genitourinary system. UrologyRC870-923ENJournal of Nephropharmacology, Vol 10, Iss 1, Pp e08-e08 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	glucoherb diabetes mellitus fasting blood sugar glycated hemoglobin metformin pre-diabetic Therapeutics. Pharmacology RM1-950 Diseases of the genitourinary system. Urology RC870-923
spellingShingle	glucoherb diabetes mellitus fasting blood sugar glycated hemoglobin metformin pre-diabetic Therapeutics. Pharmacology RM1-950 Diseases of the genitourinary system. Urology RC870-923 Iman Izadi Rahil Riahi Samani Afsaneh Malekpour Tehrani Marziyeh Dehghani Alireza Jafari Glucoherb versus metformin on glycemic markers and glycosylated hemoglobin in prediabetes patients; a clinical trial study
description	Introduction: There is a high risk of diabetes mellitus in pre-diabetic patients. Objectives: The aim of the study was to compare the effect of the extracts of these herbs in the formulation of Glucoherb supplementation versus metformin in pre-diabetes patients on glycemic markers and glycosylated hemoglobin. Patients and Methods: Pre-diabetic patients who had indication of drug treatment according to the criteria of the American Diabetes Association, were selected and randomly divided into two groups of Glucoherb and metformin. Body mass index (BMI), fasting blood sugar (FBS), 2 hours postprandial blood glucose (BS2PP) and glycosylated hemoglobin (HbA1c) were measured before and after the intervention. Results: The mean BMI, FBS, BS2PP and HbA1c levels were significantly decreased after intervention in both Glucoherb and metformin groups (P < 0.05) without any significant difference between them (P < 0.05). Conclusion: Glucoherb showed similar efficacy to metformin in reducing blood glucose, BMI and HbA1c in pre-diabetic patients.
format	article
author	Iman Izadi Rahil Riahi Samani Afsaneh Malekpour Tehrani Marziyeh Dehghani Alireza Jafari
author_facet	Iman Izadi Rahil Riahi Samani Afsaneh Malekpour Tehrani Marziyeh Dehghani Alireza Jafari
author_sort	Iman Izadi
title	Glucoherb versus metformin on glycemic markers and glycosylated hemoglobin in prediabetes patients; a clinical trial study
title_short	Glucoherb versus metformin on glycemic markers and glycosylated hemoglobin in prediabetes patients; a clinical trial study
title_full	Glucoherb versus metformin on glycemic markers and glycosylated hemoglobin in prediabetes patients; a clinical trial study
title_fullStr	Glucoherb versus metformin on glycemic markers and glycosylated hemoglobin in prediabetes patients; a clinical trial study
title_full_unstemmed	Glucoherb versus metformin on glycemic markers and glycosylated hemoglobin in prediabetes patients; a clinical trial study
title_sort	glucoherb versus metformin on glycemic markers and glycosylated hemoglobin in prediabetes patients; a clinical trial study
publisher	Society of Diabetic Nephropathy Prevention
publishDate	2021
url	https://doaj.org/article/4f81519ec97947639259be090a07edb1
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Glucoherb versus metformin on glycemic markers and glycosylated hemoglobin in prediabetes patients; a clinical trial study

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