Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships

Manuel Garcia-Medina1, Jose Javier Garcia-Medina2,3, Pablo Garrido-Fernandez1, Jose Galvan-Espinosa1, Jesus Martin-Molina1, Carlos Garcia-Maturana4, Sergio Perez-Pardo1, Maria Dolores Pinazo-Duran3 1Department of Ophthalmology, Torrecardenas Hospital, Almeria, Spain; 2Department of Ophthalmology, Hu...

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Autores principales: Manuel Garcia-Medina, Jose Javier Garcia-Medina, Pablo Garrido-Fernandez, et al
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Publicado: Dove Medical Press 2011
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spelling oai:doaj.org-article:4f8a8a6c30e545f7a3486e2ce999a0062021-12-02T03:24:54ZCentral corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships1177-54671177-5483https://doaj.org/article/4f8a8a6c30e545f7a3486e2ce999a0062011-02-01T00:00:00Zhttp://www.dovepress.com/central-corneal-thickness-intraocular-pressure-and-degree-of-myopia-in-a6483https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Manuel Garcia-Medina1, Jose Javier Garcia-Medina2,3, Pablo Garrido-Fernandez1, Jose Galvan-Espinosa1, Jesus Martin-Molina1, Carlos Garcia-Maturana4, Sergio Perez-Pardo1, Maria Dolores Pinazo-Duran3 1Department of Ophthalmology, Torrecardenas Hospital, Almeria, Spain; 2Department of Ophthalmology, Huercal Overa Hospital, Almeria, Spain; 3Ophthalmology Research Unit “Santiago Grisolia”, University Hospital Doctor Peset, Valencia, Spain; 4University of Sevilla, SpainObjective: To determine the values of, and study the relationships among, central corneal thickness (CCT), intraocular pressure (IOP), and degree of myopia (DM) in an adult myopic population aged 20 to 40 years in Almeria (southeast Spain). To our knowledge this is first study of this kind in this region.Methods: An observational, descriptive, cross-sectional study was done in which a sample of 310 myopic patients (620 eyes) aged 20 to 40 years was selected by gender- and age-stratified sampling, which was proportionally fixed to the size of the population strata for which a 20% prevalence of myopia, 5% epsilon, and a 95% confidence interval were hypothesized. We studied IOP, CCT, and DM and their relationships by calculating the mean, standard deviation, 95% confidence interval for the mean, median, Fisher’s asymmetry coefficient, range (maximum, minimum), and the Brown-Forsythe’s robust test for each variable (IOP, CCT, and DM).Results: In the adult myopic population of Almeria aged 20 to 40 years (mean of 29.8), the mean overall CCT was 550.12 µm. The corneas of men were thicker than those of women (P = 0.014). CCT was stable as no significant differences were seen in the 20- to 40-year-old subjects’ CCT values. The mean overall IOP was 13.60 mmHg. Men had a higher IOP than women (P = 0.002). Subjects over 30 years (13.83) had a higher IOP than those under 30 (13.38) (P = 0.04). The mean overall DM was -4.18 diopters. Men had less myopia than women (P < 0.001). Myopia was stable in the 20- to 40-year-old study population (P = 0.089). A linear relationship was found between CCT and IOP (R2 = 0.152, P ≤ 0.001). CCT influenced the IOP value by 15.2%. However no linear relationship between DM and IOP, or between CCT and DM, was found.Conclusions: CCT was found to be similar to that reported in other studies in different populations. IOP tends to increase after the age of 30 and is not accounted for by alterations in CCT values.Keywords: central corneal thickness, intraocular pressure, myopia, population study, glaucoma Manuel Garcia-MedinaJose Javier Garcia-MedinaPablo Garrido-Fernandezet alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 249-258 (2011)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Manuel Garcia-Medina
Jose Javier Garcia-Medina
Pablo Garrido-Fernandez
et al
Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships
description Manuel Garcia-Medina1, Jose Javier Garcia-Medina2,3, Pablo Garrido-Fernandez1, Jose Galvan-Espinosa1, Jesus Martin-Molina1, Carlos Garcia-Maturana4, Sergio Perez-Pardo1, Maria Dolores Pinazo-Duran3 1Department of Ophthalmology, Torrecardenas Hospital, Almeria, Spain; 2Department of Ophthalmology, Huercal Overa Hospital, Almeria, Spain; 3Ophthalmology Research Unit “Santiago Grisolia”, University Hospital Doctor Peset, Valencia, Spain; 4University of Sevilla, SpainObjective: To determine the values of, and study the relationships among, central corneal thickness (CCT), intraocular pressure (IOP), and degree of myopia (DM) in an adult myopic population aged 20 to 40 years in Almeria (southeast Spain). To our knowledge this is first study of this kind in this region.Methods: An observational, descriptive, cross-sectional study was done in which a sample of 310 myopic patients (620 eyes) aged 20 to 40 years was selected by gender- and age-stratified sampling, which was proportionally fixed to the size of the population strata for which a 20% prevalence of myopia, 5% epsilon, and a 95% confidence interval were hypothesized. We studied IOP, CCT, and DM and their relationships by calculating the mean, standard deviation, 95% confidence interval for the mean, median, Fisher’s asymmetry coefficient, range (maximum, minimum), and the Brown-Forsythe’s robust test for each variable (IOP, CCT, and DM).Results: In the adult myopic population of Almeria aged 20 to 40 years (mean of 29.8), the mean overall CCT was 550.12 µm. The corneas of men were thicker than those of women (P = 0.014). CCT was stable as no significant differences were seen in the 20- to 40-year-old subjects’ CCT values. The mean overall IOP was 13.60 mmHg. Men had a higher IOP than women (P = 0.002). Subjects over 30 years (13.83) had a higher IOP than those under 30 (13.38) (P = 0.04). The mean overall DM was -4.18 diopters. Men had less myopia than women (P < 0.001). Myopia was stable in the 20- to 40-year-old study population (P = 0.089). A linear relationship was found between CCT and IOP (R2 = 0.152, P ≤ 0.001). CCT influenced the IOP value by 15.2%. However no linear relationship between DM and IOP, or between CCT and DM, was found.Conclusions: CCT was found to be similar to that reported in other studies in different populations. IOP tends to increase after the age of 30 and is not accounted for by alterations in CCT values.Keywords: central corneal thickness, intraocular pressure, myopia, population study, glaucoma
format article
author Manuel Garcia-Medina
Jose Javier Garcia-Medina
Pablo Garrido-Fernandez
et al
author_facet Manuel Garcia-Medina
Jose Javier Garcia-Medina
Pablo Garrido-Fernandez
et al
author_sort Manuel Garcia-Medina
title Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships
title_short Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships
title_full Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships
title_fullStr Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships
title_full_unstemmed Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships
title_sort central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast spain: determination and relationships
publisher Dove Medical Press
publishDate 2011
url https://doaj.org/article/4f8a8a6c30e545f7a3486e2ce999a006
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