Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia
Waldenström macroglobulinemia (WM)/lymphoplasmacytic lymphoma (LPL) is a non-Hodgkin-type B cell lymphoma. Here, the authors identify two risk loci for WM/LPL in a two-stage GWAS involving a family-oversampling approach and provide evidence for a functional role of the non-coding SNP rs116446171.
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2018
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oai:doaj.org-article:4f8f4ed337f247598d7a3f86722ba5902021-12-02T15:33:44ZTwo high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia10.1038/s41467-018-06541-22041-1723https://doaj.org/article/4f8f4ed337f247598d7a3f86722ba5902018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06541-2https://doaj.org/toc/2041-1723Waldenström macroglobulinemia (WM)/lymphoplasmacytic lymphoma (LPL) is a non-Hodgkin-type B cell lymphoma. Here, the authors identify two risk loci for WM/LPL in a two-stage GWAS involving a family-oversampling approach and provide evidence for a functional role of the non-coding SNP rs116446171.Mary L. McMasterSonja I. BerndtJianqing ZhangSusan L. SlagerShengchao Alfred LiClaire M. VajdicKarin E. SmedbyHuihuang YanBrenda M. BirmannElizabeth E. BrownAlex SmithGeffen KleinsternMervin M. FanslerChristine MayrBin ZhuCharles C. ChungJu-Hyun ParkLaurie BurdetteBelynda D. HicksAmy HutchinsonLauren R. TerasHans-Olov AdamiPaige M. BracciJames McKayAlain MonnereauBrian K. LinkRoel C. H. VermeulenStephen M. AnsellAnn MariaW. Ryan DiverMads MelbyeAkinyemi I. OjesinaPeter KraftPaolo BoffettaJacqueline ClavelEdward GiovannucciCaroline M. BessonFederico CanzianRuth C. TravisPaolo VineisElisabete WeiderpassRebecca MontalvanZhaoming WangMeredith YeagerNikolaus BeckerYolanda BenaventePaul BrennanLenka ForetovaMarc MaynadieAlexandra NietersSilvia de SanjoseAnthony StainesLucia CondeJacques RibyBengt GlimeliusHenrik HjalgrimNisha PradhanAndrew L. FeldmanAnne J. NovakCharles LawrenceBryan A. BassigQing LanTongzhang ZhengKari E. NorthLesley F. TinkerWendy CozenRichard K. SeversonJonathan N. HofmannYawei ZhangRebecca D. JacksonLindsay M. MortonMark P. PurdueNilanjan ChatterjeeKenneth OffitJames R. CerhanStephen J. ChanockNathaniel RothmanJoseph VijaiLynn R. GoldinChristine F. SkibolaNeil E. CaporasoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Mary L. McMaster Sonja I. Berndt Jianqing Zhang Susan L. Slager Shengchao Alfred Li Claire M. Vajdic Karin E. Smedby Huihuang Yan Brenda M. Birmann Elizabeth E. Brown Alex Smith Geffen Kleinstern Mervin M. Fansler Christine Mayr Bin Zhu Charles C. Chung Ju-Hyun Park Laurie Burdette Belynda D. Hicks Amy Hutchinson Lauren R. Teras Hans-Olov Adami Paige M. Bracci James McKay Alain Monnereau Brian K. Link Roel C. H. Vermeulen Stephen M. Ansell Ann Maria W. Ryan Diver Mads Melbye Akinyemi I. Ojesina Peter Kraft Paolo Boffetta Jacqueline Clavel Edward Giovannucci Caroline M. Besson Federico Canzian Ruth C. Travis Paolo Vineis Elisabete Weiderpass Rebecca Montalvan Zhaoming Wang Meredith Yeager Nikolaus Becker Yolanda Benavente Paul Brennan Lenka Foretova Marc Maynadie Alexandra Nieters Silvia de Sanjose Anthony Staines Lucia Conde Jacques Riby Bengt Glimelius Henrik Hjalgrim Nisha Pradhan Andrew L. Feldman Anne J. Novak Charles Lawrence Bryan A. Bassig Qing Lan Tongzhang Zheng Kari E. North Lesley F. Tinker Wendy Cozen Richard K. Severson Jonathan N. Hofmann Yawei Zhang Rebecca D. Jackson Lindsay M. Morton Mark P. Purdue Nilanjan Chatterjee Kenneth Offit James R. Cerhan Stephen J. Chanock Nathaniel Rothman Joseph Vijai Lynn R. Goldin Christine F. Skibola Neil E. Caporaso Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia |
| description |
Waldenström macroglobulinemia (WM)/lymphoplasmacytic lymphoma (LPL) is a non-Hodgkin-type B cell lymphoma. Here, the authors identify two risk loci for WM/LPL in a two-stage GWAS involving a family-oversampling approach and provide evidence for a functional role of the non-coding SNP rs116446171. |
| format |
article |
| author |
Mary L. McMaster Sonja I. Berndt Jianqing Zhang Susan L. Slager Shengchao Alfred Li Claire M. Vajdic Karin E. Smedby Huihuang Yan Brenda M. Birmann Elizabeth E. Brown Alex Smith Geffen Kleinstern Mervin M. Fansler Christine Mayr Bin Zhu Charles C. Chung Ju-Hyun Park Laurie Burdette Belynda D. Hicks Amy Hutchinson Lauren R. Teras Hans-Olov Adami Paige M. Bracci James McKay Alain Monnereau Brian K. Link Roel C. H. Vermeulen Stephen M. Ansell Ann Maria W. Ryan Diver Mads Melbye Akinyemi I. Ojesina Peter Kraft Paolo Boffetta Jacqueline Clavel Edward Giovannucci Caroline M. Besson Federico Canzian Ruth C. Travis Paolo Vineis Elisabete Weiderpass Rebecca Montalvan Zhaoming Wang Meredith Yeager Nikolaus Becker Yolanda Benavente Paul Brennan Lenka Foretova Marc Maynadie Alexandra Nieters Silvia de Sanjose Anthony Staines Lucia Conde Jacques Riby Bengt Glimelius Henrik Hjalgrim Nisha Pradhan Andrew L. Feldman Anne J. Novak Charles Lawrence Bryan A. Bassig Qing Lan Tongzhang Zheng Kari E. North Lesley F. Tinker Wendy Cozen Richard K. Severson Jonathan N. Hofmann Yawei Zhang Rebecca D. Jackson Lindsay M. Morton Mark P. Purdue Nilanjan Chatterjee Kenneth Offit James R. Cerhan Stephen J. Chanock Nathaniel Rothman Joseph Vijai Lynn R. Goldin Christine F. Skibola Neil E. Caporaso |
| author_facet |
Mary L. McMaster Sonja I. Berndt Jianqing Zhang Susan L. Slager Shengchao Alfred Li Claire M. Vajdic Karin E. Smedby Huihuang Yan Brenda M. Birmann Elizabeth E. Brown Alex Smith Geffen Kleinstern Mervin M. Fansler Christine Mayr Bin Zhu Charles C. Chung Ju-Hyun Park Laurie Burdette Belynda D. Hicks Amy Hutchinson Lauren R. Teras Hans-Olov Adami Paige M. Bracci James McKay Alain Monnereau Brian K. Link Roel C. H. Vermeulen Stephen M. Ansell Ann Maria W. Ryan Diver Mads Melbye Akinyemi I. Ojesina Peter Kraft Paolo Boffetta Jacqueline Clavel Edward Giovannucci Caroline M. Besson Federico Canzian Ruth C. Travis Paolo Vineis Elisabete Weiderpass Rebecca Montalvan Zhaoming Wang Meredith Yeager Nikolaus Becker Yolanda Benavente Paul Brennan Lenka Foretova Marc Maynadie Alexandra Nieters Silvia de Sanjose Anthony Staines Lucia Conde Jacques Riby Bengt Glimelius Henrik Hjalgrim Nisha Pradhan Andrew L. Feldman Anne J. Novak Charles Lawrence Bryan A. Bassig Qing Lan Tongzhang Zheng Kari E. North Lesley F. Tinker Wendy Cozen Richard K. Severson Jonathan N. Hofmann Yawei Zhang Rebecca D. Jackson Lindsay M. Morton Mark P. Purdue Nilanjan Chatterjee Kenneth Offit James R. Cerhan Stephen J. Chanock Nathaniel Rothman Joseph Vijai Lynn R. Goldin Christine F. Skibola Neil E. Caporaso |
| author_sort |
Mary L. McMaster |
| title |
Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia |
| title_short |
Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia |
| title_full |
Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia |
| title_fullStr |
Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia |
| title_full_unstemmed |
Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia |
| title_sort |
two high-risk susceptibility loci at 6p25.3 and 14q32.13 for waldenström macroglobulinemia |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/4f8f4ed337f247598d7a3f86722ba590 |
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