Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B

We recently published a report validating point-of-care rapid diagnostic tests (RDT) for the diagnosis of Hepatitis B virus (HBV) infection in serum. In the current report, we validated a whole-blood RDT for HBsAg in the form of a test-strip. The test was validated in 55 HBV positive individuals acr...

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Autores principales:	Jose D. Debes, Gertine van Oord, Andre Boonstra
Formato:	article
Lenguaje:	EN
Publicado:	Ubiquity Press 2020
Materias:	Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/4f8fa87fd57848399e8052c347a55a4a
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spelling	oai:doaj.org-article:4f8fa87fd57848399e8052c347a55a4a2021-12-02T09:33:07ZValidation of Whole Blood Rapid Diagnosis Test for Hepatitis B2214-999610.5334/aogh.2866https://doaj.org/article/4f8fa87fd57848399e8052c347a55a4a2020-05-01T00:00:00Zhttps://annalsofglobalhealth.org/articles/2866https://doaj.org/toc/2214-9996We recently published a report validating point-of-care rapid diagnostic tests (RDT) for the diagnosis of Hepatitis B virus (HBV) infection in serum. In the current report, we validated a whole-blood RDT for HBsAg in the form of a test-strip. The test was validated in 55 HBV positive individuals across all genotypes other than F, and in 20 HBV negative individuals in the Netherlands. The RDT showed 100% sensitivity and specificity. The low cost and use in whole blood allows this RDT to be useful in resource-limited locations, further validation in such settings will be of importance.Jose D. DebesGertine van OordAndre BoonstraUbiquity PressarticleInfectious and parasitic diseasesRC109-216Public aspects of medicineRA1-1270ENAnnals of Global Health, Vol 86, Iss 1 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
spellingShingle	Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270 Jose D. Debes Gertine van Oord Andre Boonstra Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B
description	We recently published a report validating point-of-care rapid diagnostic tests (RDT) for the diagnosis of Hepatitis B virus (HBV) infection in serum. In the current report, we validated a whole-blood RDT for HBsAg in the form of a test-strip. The test was validated in 55 HBV positive individuals across all genotypes other than F, and in 20 HBV negative individuals in the Netherlands. The RDT showed 100% sensitivity and specificity. The low cost and use in whole blood allows this RDT to be useful in resource-limited locations, further validation in such settings will be of importance.
format	article
author	Jose D. Debes Gertine van Oord Andre Boonstra
author_facet	Jose D. Debes Gertine van Oord Andre Boonstra
author_sort	Jose D. Debes
title	Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B
title_short	Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B
title_full	Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B
title_fullStr	Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B
title_full_unstemmed	Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B
title_sort	validation of whole blood rapid diagnosis test for hepatitis b
publisher	Ubiquity Press
publishDate	2020
url	https://doaj.org/article/4f8fa87fd57848399e8052c347a55a4a
work_keys_str_mv	AT joseddebes validationofwholebloodrapiddiagnosistestforhepatitisb AT gertinevanoord validationofwholebloodrapiddiagnosistestforhepatitisb AT andreboonstra validationofwholebloodrapiddiagnosistestforhepatitisb
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Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B

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