Cerebral germinoma revealed through a polydipsic polyuric syndrome in a 10-year-old girl: case report

Cerebral germinoma is rare. Although the imaging of the germinoma is very evocative, it’s very polymorphic clinical expression is at the origin of misguided diagnosis, as illustrated in our case. We report the case of a 10-year-old girl with diabetes insipidus evolving for 12 months associated with...

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Autores principales:	Van Lierde, Clapuyt P., Nassogne M. C., Oriot Philippe
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2017
Materias:	diabetes insipidus panhypopituitarism intracerebral germinoma Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/4f9d10013b2547f494ca5dfbc5891922
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spelling	oai:doaj.org-article:4f9d10013b2547f494ca5dfbc58919222021-12-02T19:10:31ZCerebral germinoma revealed through a polydipsic polyuric syndrome in a 10-year-old girl: case report1336-032910.1515/enr-2017-0023https://doaj.org/article/4f9d10013b2547f494ca5dfbc58919222017-10-01T00:00:00Zhttps://doi.org/10.1515/enr-2017-0023https://doaj.org/toc/1336-0329Cerebral germinoma is rare. Although the imaging of the germinoma is very evocative, it’s very polymorphic clinical expression is at the origin of misguided diagnosis, as illustrated in our case. We report the case of a 10-year-old girl with diabetes insipidus evolving for 12 months associated with a decrease in visual acuity. Brain MRI (Magnetic Resonance Imaging) revealed a tumor process in the suprasellar region. The stereotaxic biopsy of the tumor confirmed the diagnosis of the hypothalamic germinoma, which allowed the patient to be treated by radiotherapy and chemotherapy. The incidence of cerebral germinoma, its clinical (principally diabetes insipidus) and radiological features as well as therapeutic strategies are discussed hereby.Van LierdeClapuyt P.Nassogne M. C.Oriot PhilippeSciendoarticlediabetes insipiduspanhypopituitarismintracerebral germinomaDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 51, Iss 4, Pp 216-219 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	diabetes insipidus panhypopituitarism intracerebral germinoma Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	diabetes insipidus panhypopituitarism intracerebral germinoma Diseases of the endocrine glands. Clinical endocrinology RC648-665 Van Lierde Clapuyt P. Nassogne M. C. Oriot Philippe Cerebral germinoma revealed through a polydipsic polyuric syndrome in a 10-year-old girl: case report
description	Cerebral germinoma is rare. Although the imaging of the germinoma is very evocative, it’s very polymorphic clinical expression is at the origin of misguided diagnosis, as illustrated in our case. We report the case of a 10-year-old girl with diabetes insipidus evolving for 12 months associated with a decrease in visual acuity. Brain MRI (Magnetic Resonance Imaging) revealed a tumor process in the suprasellar region. The stereotaxic biopsy of the tumor confirmed the diagnosis of the hypothalamic germinoma, which allowed the patient to be treated by radiotherapy and chemotherapy. The incidence of cerebral germinoma, its clinical (principally diabetes insipidus) and radiological features as well as therapeutic strategies are discussed hereby.
format	article
author	Van Lierde Clapuyt P. Nassogne M. C. Oriot Philippe
author_facet	Van Lierde Clapuyt P. Nassogne M. C. Oriot Philippe
author_sort	Van Lierde
title	Cerebral germinoma revealed through a polydipsic polyuric syndrome in a 10-year-old girl: case report
title_short	Cerebral germinoma revealed through a polydipsic polyuric syndrome in a 10-year-old girl: case report
title_full	Cerebral germinoma revealed through a polydipsic polyuric syndrome in a 10-year-old girl: case report
title_fullStr	Cerebral germinoma revealed through a polydipsic polyuric syndrome in a 10-year-old girl: case report
title_full_unstemmed	Cerebral germinoma revealed through a polydipsic polyuric syndrome in a 10-year-old girl: case report
title_sort	cerebral germinoma revealed through a polydipsic polyuric syndrome in a 10-year-old girl: case report
publisher	Sciendo
publishDate	2017
url	https://doaj.org/article/4f9d10013b2547f494ca5dfbc5891922
work_keys_str_mv	AT vanlierde cerebralgerminomarevealedthroughapolydipsicpolyuricsyndromeina10yearoldgirlcasereport AT clapuytp cerebralgerminomarevealedthroughapolydipsicpolyuricsyndromeina10yearoldgirlcasereport AT nassognemc cerebralgerminomarevealedthroughapolydipsicpolyuricsyndromeina10yearoldgirlcasereport AT oriotphilippe cerebralgerminomarevealedthroughapolydipsicpolyuricsyndromeina10yearoldgirlcasereport
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Cerebral germinoma revealed through a polydipsic polyuric syndrome in a 10-year-old girl: case report

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