Covalent α-synuclein dimers: chemico-physical and aggregation properties.

Covalent α-synuclein dimers: chemico-physical and aggregation properties.

The aggregation of α-synuclein into amyloid fibrils constitutes a key step in the onset of Parkinson's disease. Amyloid fibrils of α-synuclein are the major component of Lewy bodies, histological hallmarks of the disease. Little is known about the mechanism of aggregation of α-synuclein. During...

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Autores principales: Micaela Pivato, Giorgia De Franceschi, Laura Tosatto, Erica Frare, Dhruv Kumar, Daniel Aioanei, Marco Brucale, Isabella Tessari, Marco Bisaglia, Bruno Samori, Patrizia Polverino de Laureto, Luigi Bubacco
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/4f9e6ddc81bf4a3ab85ffa09db79fc64
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