Conserved phosphorylation hotspots in eukaryotic protein domain families
Protein phosphorylation has various regulatory functions. Here, the authors map 241 phosphorylation hotspot regions across 40 eukaryotic species, showing that they are enriched at interfaces and near catalytic residues, and enable the discovery of functionally important phospho-sites.
Guardado en:
Autores principales: | Marta J. Strumillo, Michaela Oplová, Cristina Viéitez, David Ochoa, Mohammed Shahraz, Bede P. Busby, Richelle Sopko, Romain A. Studer, Norbert Perrimon, Vikram G. Panse, Pedro Beltrao |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/4fa001d5e18b4538b71b32f9cc484470 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Global diversity hotspots and conservation priorities for sharks.
por: Luis O Lucifora, et al.
Publicado: (2011) -
Small patches are hotspots for biodiversity conservation in fragmented landscapes
por: Yongzhi Yan, et al.
Publicado: (2021) -
Polyglutamine repeats are associated to specific sequence biases that are conserved among eukaryotes.
por: Matteo Ramazzotti, et al.
Publicado: (2012) -
Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2
por: Sabina Schütz, et al.
Publicado: (2018) -
Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E
por: Argel Aguilar-Valles, et al.
Publicado: (2018)