The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation

Temporary association of metabolic enzymes is generally assumed to facilitate substrate channelling within the complex. In this review, Lee Sweetlove and Alisdair Fernie outline the nature and functional consequence of organising enzymes into assemblies, and discuss applications within the natural w...

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Auteurs principaux: Lee J. Sweetlove, Alisdair R. Fernie
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/4fa407f3b44d4057929a68ccee058b60
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spelling oai:doaj.org-article:4fa407f3b44d4057929a68ccee058b602021-12-02T14:39:09ZThe role of dynamic enzyme assemblies and substrate channelling in metabolic regulation10.1038/s41467-018-04543-82041-1723https://doaj.org/article/4fa407f3b44d4057929a68ccee058b602018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04543-8https://doaj.org/toc/2041-1723Temporary association of metabolic enzymes is generally assumed to facilitate substrate channelling within the complex. In this review, Lee Sweetlove and Alisdair Fernie outline the nature and functional consequence of organising enzymes into assemblies, and discuss applications within the natural world and synthetic biology.Lee J. SweetloveAlisdair R. FernieNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lee J. Sweetlove
Alisdair R. Fernie
The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation
description Temporary association of metabolic enzymes is generally assumed to facilitate substrate channelling within the complex. In this review, Lee Sweetlove and Alisdair Fernie outline the nature and functional consequence of organising enzymes into assemblies, and discuss applications within the natural world and synthetic biology.
format article
author Lee J. Sweetlove
Alisdair R. Fernie
author_facet Lee J. Sweetlove
Alisdair R. Fernie
author_sort Lee J. Sweetlove
title The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation
title_short The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation
title_full The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation
title_fullStr The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation
title_full_unstemmed The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation
title_sort role of dynamic enzyme assemblies and substrate channelling in metabolic regulation
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/4fa407f3b44d4057929a68ccee058b60
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