The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation
Temporary association of metabolic enzymes is generally assumed to facilitate substrate channelling within the complex. In this review, Lee Sweetlove and Alisdair Fernie outline the nature and functional consequence of organising enzymes into assemblies, and discuss applications within the natural w...
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2018
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oai:doaj.org-article:4fa407f3b44d4057929a68ccee058b602021-12-02T14:39:09ZThe role of dynamic enzyme assemblies and substrate channelling in metabolic regulation10.1038/s41467-018-04543-82041-1723https://doaj.org/article/4fa407f3b44d4057929a68ccee058b602018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04543-8https://doaj.org/toc/2041-1723Temporary association of metabolic enzymes is generally assumed to facilitate substrate channelling within the complex. In this review, Lee Sweetlove and Alisdair Fernie outline the nature and functional consequence of organising enzymes into assemblies, and discuss applications within the natural world and synthetic biology.Lee J. SweetloveAlisdair R. FernieNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q Lee J. Sweetlove Alisdair R. Fernie The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation |
description |
Temporary association of metabolic enzymes is generally assumed to facilitate substrate channelling within the complex. In this review, Lee Sweetlove and Alisdair Fernie outline the nature and functional consequence of organising enzymes into assemblies, and discuss applications within the natural world and synthetic biology. |
format |
article |
author |
Lee J. Sweetlove Alisdair R. Fernie |
author_facet |
Lee J. Sweetlove Alisdair R. Fernie |
author_sort |
Lee J. Sweetlove |
title |
The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation |
title_short |
The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation |
title_full |
The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation |
title_fullStr |
The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation |
title_full_unstemmed |
The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation |
title_sort |
role of dynamic enzyme assemblies and substrate channelling in metabolic regulation |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/4fa407f3b44d4057929a68ccee058b60 |
work_keys_str_mv |
AT leejsweetlove theroleofdynamicenzymeassembliesandsubstratechannellinginmetabolicregulation AT alisdairrfernie theroleofdynamicenzymeassembliesandsubstratechannellinginmetabolicregulation AT leejsweetlove roleofdynamicenzymeassembliesandsubstratechannellinginmetabolicregulation AT alisdairrfernie roleofdynamicenzymeassembliesandsubstratechannellinginmetabolicregulation |
_version_ |
1718390711777230848 |