Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly

Topoisomerase IIα (topo IIα) is critical for mitotic chromatid assembly. Here the authors report a refinement of the mitotic chromatid reconstitution assay and provide novel insights into the C-terminal domain (CTD) of topo IIα.

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Autores principales:	Keishi Shintomi, Tatsuya Hirano
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4fa40d26a1d8472bbd2c5f3ef0c0d839
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spelling	oai:doaj.org-article:4fa40d26a1d8472bbd2c5f3ef0c0d8392021-12-02T14:58:51ZGuiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly10.1038/s41467-021-23205-w2041-1723https://doaj.org/article/4fa40d26a1d8472bbd2c5f3ef0c0d8392021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23205-whttps://doaj.org/toc/2041-1723Topoisomerase IIα (topo IIα) is critical for mitotic chromatid assembly. Here the authors report a refinement of the mitotic chromatid reconstitution assay and provide novel insights into the C-terminal domain (CTD) of topo IIα.Keishi ShintomiTatsuya HiranoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Keishi Shintomi Tatsuya Hirano Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly
description	Topoisomerase IIα (topo IIα) is critical for mitotic chromatid assembly. Here the authors report a refinement of the mitotic chromatid reconstitution assay and provide novel insights into the C-terminal domain (CTD) of topo IIα.
format	article
author	Keishi Shintomi Tatsuya Hirano
author_facet	Keishi Shintomi Tatsuya Hirano
author_sort	Keishi Shintomi
title	Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly
title_short	Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly
title_full	Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly
title_fullStr	Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly
title_full_unstemmed	Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly
title_sort	guiding functions of the c-terminal domain of topoisomerase iiα advance mitotic chromosome assembly
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4fa40d26a1d8472bbd2c5f3ef0c0d839
work_keys_str_mv	AT keishishintomi guidingfunctionsofthecterminaldomainoftopoisomeraseiiaadvancemitoticchromosomeassembly AT tatsuyahirano guidingfunctionsofthecterminaldomainoftopoisomeraseiiaadvancemitoticchromosomeassembly
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Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly

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