Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly

Topoisomerase IIα (topo IIα) is critical for mitotic chromatid assembly. Here the authors report a refinement of the mitotic chromatid reconstitution assay and provide novel insights into the C-terminal domain (CTD) of topo IIα.

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Bibliographic Details
Main Authors: Keishi Shintomi, Tatsuya Hirano
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/4fa40d26a1d8472bbd2c5f3ef0c0d839
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