Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly
Topoisomerase IIα (topo IIα) is critical for mitotic chromatid assembly. Here the authors report a refinement of the mitotic chromatid reconstitution assay and provide novel insights into the C-terminal domain (CTD) of topo IIα.
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Autores principales: | Keishi Shintomi, Tatsuya Hirano |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/4fa40d26a1d8472bbd2c5f3ef0c0d839 |
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