Neuronal processes and glial precursors form a scaffold for wiring the developing mouse cochlea

Neuronal processes and glial precursors form a scaffold for wiring the developing mouse cochlea

In developing embryos, axons grow through complex and dynamic terrains. Here, the authors show that spiral ganglion neurons in the developing mouse cochlea extend leading axons that interact with a scaffold of glial precursors, with follower axons fasciculating on top.

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Autores principales: N. R. Druckenbrod, E. B. Hale, O. O. Olukoya, W. E. Shatzer, L. V. Goodrich
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/4fb40d5258fd4590abcfd69b0403c8e3
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spelling oai:doaj.org-article:4fb40d5258fd4590abcfd69b0403c8e32021-12-02T16:56:52ZNeuronal processes and glial precursors form a scaffold for wiring the developing mouse cochlea10.1038/s41467-020-19521-22041-1723https://doaj.org/article/4fb40d5258fd4590abcfd69b0403c8e32020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19521-2https://doaj.org/toc/2041-1723In developing embryos, axons grow through complex and dynamic terrains. Here, the authors show that spiral ganglion neurons in the developing mouse cochlea extend leading axons that interact with a scaffold of glial precursors, with follower axons fasciculating on top.N. R. DruckenbrodE. B. HaleO. O. OlukoyaW. E. ShatzerL. V. GoodrichNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
N. R. Druckenbrod
E. B. Hale
O. O. Olukoya
W. E. Shatzer
L. V. Goodrich
Neuronal processes and glial precursors form a scaffold for wiring the developing mouse cochlea
description In developing embryos, axons grow through complex and dynamic terrains. Here, the authors show that spiral ganglion neurons in the developing mouse cochlea extend leading axons that interact with a scaffold of glial precursors, with follower axons fasciculating on top.
format article
author N. R. Druckenbrod
E. B. Hale
O. O. Olukoya
W. E. Shatzer
L. V. Goodrich
author_facet N. R. Druckenbrod
E. B. Hale
O. O. Olukoya
W. E. Shatzer
L. V. Goodrich
author_sort N. R. Druckenbrod
title Neuronal processes and glial precursors form a scaffold for wiring the developing mouse cochlea
title_short Neuronal processes and glial precursors form a scaffold for wiring the developing mouse cochlea
title_full Neuronal processes and glial precursors form a scaffold for wiring the developing mouse cochlea
title_fullStr Neuronal processes and glial precursors form a scaffold for wiring the developing mouse cochlea
title_full_unstemmed Neuronal processes and glial precursors form a scaffold for wiring the developing mouse cochlea
title_sort neuronal processes and glial precursors form a scaffold for wiring the developing mouse cochlea
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/4fb40d5258fd4590abcfd69b0403c8e3
work_keys_str_mv AT nrdruckenbrod neuronalprocessesandglialprecursorsformascaffoldforwiringthedevelopingmousecochlea
AT ebhale neuronalprocessesandglialprecursorsformascaffoldforwiringthedevelopingmousecochlea
AT ooolukoya neuronalprocessesandglialprecursorsformascaffoldforwiringthedevelopingmousecochlea
AT weshatzer neuronalprocessesandglialprecursorsformascaffoldforwiringthedevelopingmousecochlea
AT lvgoodrich neuronalprocessesandglialprecursorsformascaffoldforwiringthedevelopingmousecochlea
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