Surface chemistry governs cellular tropism of nanoparticles in the brain

There have been numerous attempts to develop nanomaterials to reach cells of the central nervous system for drug delivery. Here, the authors investigate the cellular fate of polymer-based nanoparticles with varying surface chemistries after administration directly into the brain.

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Autores principales:	Eric Song, Alice Gaudin, Amanda R. King, Young-Eun Seo, Hee-Won Suh, Yang Deng, Jiajia Cui, Gregory T. Tietjen, Anita Huttner, W. Mark Saltzman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4fbea6de43b54209846ade3d250e1139
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spelling	oai:doaj.org-article:4fbea6de43b54209846ade3d250e11392021-12-02T14:42:43ZSurface chemistry governs cellular tropism of nanoparticles in the brain10.1038/ncomms153222041-1723https://doaj.org/article/4fbea6de43b54209846ade3d250e11392017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15322https://doaj.org/toc/2041-1723There have been numerous attempts to develop nanomaterials to reach cells of the central nervous system for drug delivery. Here, the authors investigate the cellular fate of polymer-based nanoparticles with varying surface chemistries after administration directly into the brain.Eric SongAlice GaudinAmanda R. KingYoung-Eun SeoHee-Won SuhYang DengJiajia CuiGregory T. TietjenAnita HuttnerW. Mark SaltzmanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Eric Song Alice Gaudin Amanda R. King Young-Eun Seo Hee-Won Suh Yang Deng Jiajia Cui Gregory T. Tietjen Anita Huttner W. Mark Saltzman Surface chemistry governs cellular tropism of nanoparticles in the brain
description	There have been numerous attempts to develop nanomaterials to reach cells of the central nervous system for drug delivery. Here, the authors investigate the cellular fate of polymer-based nanoparticles with varying surface chemistries after administration directly into the brain.
format	article
author	Eric Song Alice Gaudin Amanda R. King Young-Eun Seo Hee-Won Suh Yang Deng Jiajia Cui Gregory T. Tietjen Anita Huttner W. Mark Saltzman
author_facet	Eric Song Alice Gaudin Amanda R. King Young-Eun Seo Hee-Won Suh Yang Deng Jiajia Cui Gregory T. Tietjen Anita Huttner W. Mark Saltzman
author_sort	Eric Song
title	Surface chemistry governs cellular tropism of nanoparticles in the brain
title_short	Surface chemistry governs cellular tropism of nanoparticles in the brain
title_full	Surface chemistry governs cellular tropism of nanoparticles in the brain
title_fullStr	Surface chemistry governs cellular tropism of nanoparticles in the brain
title_full_unstemmed	Surface chemistry governs cellular tropism of nanoparticles in the brain
title_sort	surface chemistry governs cellular tropism of nanoparticles in the brain
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/4fbea6de43b54209846ade3d250e1139
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Surface chemistry governs cellular tropism of nanoparticles in the brain

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