Surface chemistry governs cellular tropism of nanoparticles in the brain

There have been numerous attempts to develop nanomaterials to reach cells of the central nervous system for drug delivery. Here, the authors investigate the cellular fate of polymer-based nanoparticles with varying surface chemistries after administration directly into the brain.

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Bibliographic Details
Main Authors: Eric Song, Alice Gaudin, Amanda R. King, Young-Eun Seo, Hee-Won Suh, Yang Deng, Jiajia Cui, Gregory T. Tietjen, Anita Huttner, W. Mark Saltzman
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/4fbea6de43b54209846ade3d250e1139
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