Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction

Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction

The miR-17-92 cluster has been shown to regulate cardiomyocyte proliferation in vitro and in genetic mutation and overexpression models. Here the authors show that the cluster member miR-19a/19b regulates cardiomyocyte proliferation in vivo, and that delivery of miR-19a/19b to the heart leads to bot...

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Autores principales: Feng Gao, Masaharu Kataoka, Ning Liu, Tian Liang, Zhan-Peng Huang, Fei Gu, Jian Ding, Jianming Liu, Feng Zhang, Qing Ma, Yingchao Wang, Mingming Zhang, Xiaoyun Hu, Jan Kyselovic, Xinyang Hu, William T. Pu, Jian’an Wang, Jinghai Chen, Da-Zhi Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/4fc1b6c932d84c21b2b0cc9b87242fbc
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