Human cortical dynamics during full-body heading changes

Abstract The retrosplenial complex (RSC) plays a crucial role in spatial orientation by computing heading direction and translating between distinct spatial reference frames based on multi-sensory information. While invasive studies allow investigating heading computation in moving animals, establis...

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Autores principales:	Klaus Gramann, Friederike U. Hohlefeld, Lukas Gehrke, Marius Klug
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4fc389b4de974c88aeed38ed3caadcf0
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id	oai:doaj.org-article:4fc389b4de974c88aeed38ed3caadcf0
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spelling	oai:doaj.org-article:4fc389b4de974c88aeed38ed3caadcf02021-12-02T18:50:52ZHuman cortical dynamics during full-body heading changes10.1038/s41598-021-97749-82045-2322https://doaj.org/article/4fc389b4de974c88aeed38ed3caadcf02021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-97749-8https://doaj.org/toc/2045-2322Abstract The retrosplenial complex (RSC) plays a crucial role in spatial orientation by computing heading direction and translating between distinct spatial reference frames based on multi-sensory information. While invasive studies allow investigating heading computation in moving animals, established non-invasive analyses of human brain dynamics are restricted to stationary setups. To investigate the role of the RSC in heading computation of actively moving humans, we used a Mobile Brain/Body Imaging approach synchronizing electroencephalography with motion capture and virtual reality. Data from physically rotating participants were contrasted with rotations based only on visual flow. During physical rotation, varying rotation velocities were accompanied by pronounced wide frequency band synchronization in RSC, the parietal and occipital cortices. In contrast, the visual flow rotation condition was associated with pronounced alpha band desynchronization, replicating previous findings in desktop navigation studies, and notably absent during physical rotation. These results suggest an involvement of the human RSC in heading computation based on visual, vestibular, and proprioceptive input and implicate revisiting traditional findings of alpha desynchronization in areas of the navigation network during spatial orientation in movement-restricted participants.Klaus GramannFriederike U. HohlefeldLukas GehrkeMarius KlugNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Klaus Gramann Friederike U. Hohlefeld Lukas Gehrke Marius Klug Human cortical dynamics during full-body heading changes
description	Abstract The retrosplenial complex (RSC) plays a crucial role in spatial orientation by computing heading direction and translating between distinct spatial reference frames based on multi-sensory information. While invasive studies allow investigating heading computation in moving animals, established non-invasive analyses of human brain dynamics are restricted to stationary setups. To investigate the role of the RSC in heading computation of actively moving humans, we used a Mobile Brain/Body Imaging approach synchronizing electroencephalography with motion capture and virtual reality. Data from physically rotating participants were contrasted with rotations based only on visual flow. During physical rotation, varying rotation velocities were accompanied by pronounced wide frequency band synchronization in RSC, the parietal and occipital cortices. In contrast, the visual flow rotation condition was associated with pronounced alpha band desynchronization, replicating previous findings in desktop navigation studies, and notably absent during physical rotation. These results suggest an involvement of the human RSC in heading computation based on visual, vestibular, and proprioceptive input and implicate revisiting traditional findings of alpha desynchronization in areas of the navigation network during spatial orientation in movement-restricted participants.
format	article
author	Klaus Gramann Friederike U. Hohlefeld Lukas Gehrke Marius Klug
author_facet	Klaus Gramann Friederike U. Hohlefeld Lukas Gehrke Marius Klug
author_sort	Klaus Gramann
title	Human cortical dynamics during full-body heading changes
title_short	Human cortical dynamics during full-body heading changes
title_full	Human cortical dynamics during full-body heading changes
title_fullStr	Human cortical dynamics during full-body heading changes
title_full_unstemmed	Human cortical dynamics during full-body heading changes
title_sort	human cortical dynamics during full-body heading changes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4fc389b4de974c88aeed38ed3caadcf0
work_keys_str_mv	AT klausgramann humancorticaldynamicsduringfullbodyheadingchanges AT friederikeuhohlefeld humancorticaldynamicsduringfullbodyheadingchanges AT lukasgehrke humancorticaldynamicsduringfullbodyheadingchanges AT mariusklug humancorticaldynamicsduringfullbodyheadingchanges
_version_	1718377502016012288

Human cortical dynamics during full-body heading changes

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