Versatile roles of V-ATPases accessory subunit Ac45 in osteoclast formation and function.

Vacuolar-type H(+)-ATPases (V-ATPases) are macromolecular proton pumps that acidify intracellular cargos and deliver protons across the plasma membrane of a variety of specialized cells, including bone-resorbing osteoclasts. Extracellular acidification is crucial for osteoclastic bone resorption, a...

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Autores principales: An Qin, Tak S Cheng, Zhen Lin, Nathan J Pavlos, Qing Jiang, Jiake Xu, Ke R Dai, Ming H Zheng
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/4fc5ed48e81d4d05a1e72eb3d2e29293
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