Rapid prototyping and design of cybergenetic single-cell controllers

Practical implementation of genetic circuits is difficult due to low predictability and time-intensive troubleshooting. Here the authors present Cyberloop, which interfaces a computer with single cells to enable cell-in-the-loop testing and optimization of circuit designs before they are built.

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Autores principales: Sant Kumar, Marc Rullan, Mustafa Khammash
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4fcf3df15f76449dadbb49cc144fd3b4
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spelling oai:doaj.org-article:4fcf3df15f76449dadbb49cc144fd3b42021-12-02T18:14:31ZRapid prototyping and design of cybergenetic single-cell controllers10.1038/s41467-021-25754-62041-1723https://doaj.org/article/4fcf3df15f76449dadbb49cc144fd3b42021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25754-6https://doaj.org/toc/2041-1723Practical implementation of genetic circuits is difficult due to low predictability and time-intensive troubleshooting. Here the authors present Cyberloop, which interfaces a computer with single cells to enable cell-in-the-loop testing and optimization of circuit designs before they are built.Sant KumarMarc RullanMustafa KhammashNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sant Kumar
Marc Rullan
Mustafa Khammash
Rapid prototyping and design of cybergenetic single-cell controllers
description Practical implementation of genetic circuits is difficult due to low predictability and time-intensive troubleshooting. Here the authors present Cyberloop, which interfaces a computer with single cells to enable cell-in-the-loop testing and optimization of circuit designs before they are built.
format article
author Sant Kumar
Marc Rullan
Mustafa Khammash
author_facet Sant Kumar
Marc Rullan
Mustafa Khammash
author_sort Sant Kumar
title Rapid prototyping and design of cybergenetic single-cell controllers
title_short Rapid prototyping and design of cybergenetic single-cell controllers
title_full Rapid prototyping and design of cybergenetic single-cell controllers
title_fullStr Rapid prototyping and design of cybergenetic single-cell controllers
title_full_unstemmed Rapid prototyping and design of cybergenetic single-cell controllers
title_sort rapid prototyping and design of cybergenetic single-cell controllers
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/4fcf3df15f76449dadbb49cc144fd3b4
work_keys_str_mv AT santkumar rapidprototypinganddesignofcybergeneticsinglecellcontrollers
AT marcrullan rapidprototypinganddesignofcybergeneticsinglecellcontrollers
AT mustafakhammash rapidprototypinganddesignofcybergeneticsinglecellcontrollers
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