Rapid prototyping and design of cybergenetic single-cell controllers
Practical implementation of genetic circuits is difficult due to low predictability and time-intensive troubleshooting. Here the authors present Cyberloop, which interfaces a computer with single cells to enable cell-in-the-loop testing and optimization of circuit designs before they are built.
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Nature Portfolio
2021
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oai:doaj.org-article:4fcf3df15f76449dadbb49cc144fd3b42021-12-02T18:14:31ZRapid prototyping and design of cybergenetic single-cell controllers10.1038/s41467-021-25754-62041-1723https://doaj.org/article/4fcf3df15f76449dadbb49cc144fd3b42021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25754-6https://doaj.org/toc/2041-1723Practical implementation of genetic circuits is difficult due to low predictability and time-intensive troubleshooting. Here the authors present Cyberloop, which interfaces a computer with single cells to enable cell-in-the-loop testing and optimization of circuit designs before they are built.Sant KumarMarc RullanMustafa KhammashNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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Science Q Sant Kumar Marc Rullan Mustafa Khammash Rapid prototyping and design of cybergenetic single-cell controllers |
description |
Practical implementation of genetic circuits is difficult due to low predictability and time-intensive troubleshooting. Here the authors present Cyberloop, which interfaces a computer with single cells to enable cell-in-the-loop testing and optimization of circuit designs before they are built. |
format |
article |
author |
Sant Kumar Marc Rullan Mustafa Khammash |
author_facet |
Sant Kumar Marc Rullan Mustafa Khammash |
author_sort |
Sant Kumar |
title |
Rapid prototyping and design of cybergenetic single-cell controllers |
title_short |
Rapid prototyping and design of cybergenetic single-cell controllers |
title_full |
Rapid prototyping and design of cybergenetic single-cell controllers |
title_fullStr |
Rapid prototyping and design of cybergenetic single-cell controllers |
title_full_unstemmed |
Rapid prototyping and design of cybergenetic single-cell controllers |
title_sort |
rapid prototyping and design of cybergenetic single-cell controllers |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/4fcf3df15f76449dadbb49cc144fd3b4 |
work_keys_str_mv |
AT santkumar rapidprototypinganddesignofcybergeneticsinglecellcontrollers AT marcrullan rapidprototypinganddesignofcybergeneticsinglecellcontrollers AT mustafakhammash rapidprototypinganddesignofcybergeneticsinglecellcontrollers |
_version_ |
1718378392488771584 |