Long bone structure and strength depend on BMP2 from osteoblasts and osteocytes, but not vascular endothelial cells.

Long bone structure and strength depend on BMP2 from osteoblasts and osteocytes, but not vascular endothelial cells.

The importance of bone morphogenetic protein 2 (BMP2) in the skeleton is well known. BMP2 is expressed in a variety of tissues during development, growth and healing. In this study we sought to better identify the role of tissue-specific BMP2 during post-natal growth and to determine if BMP2 knockou...

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Autores principales: Sarah H McBride, Jennifer A McKenzie, Bronwyn S Bedrick, Paige Kuhlmann, Jill D Pasteris, Vicki Rosen, Matthew J Silva
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/4fd0986bd2964817852b2f13f9f6516a
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