Metabolic factors that affect health-related quality of life in type 2 diabetes patients: a multivariate regression analysis

Tania Dehesh,1 Paria Dehesh,2 Mohammad Hossein Gozashti31Department of Biostatistics and Epidemiology, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran; 2Graduated of Veterinary Medicine Faculty, Shahid Bahonar University of Kerman, Kerman, Iran; 3Department of Endocrinol...

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Autores principales:	Dehesh T, Dehesh P, Gozashti MH
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Quality of Life SF-36 questionnaire metabolic variables Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/4fd4d81c1c334ec0846444b545539a03
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spelling	oai:doaj.org-article:4fd4d81c1c334ec0846444b545539a032021-12-02T01:32:29ZMetabolic factors that affect health-related quality of life in type 2 diabetes patients: a multivariate regression analysis1178-7007https://doaj.org/article/4fd4d81c1c334ec0846444b545539a032019-07-01T00:00:00Zhttps://www.dovepress.com/metabolic-factors-that-affect-health-related-quality-of-life-in-type-2-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Tania Dehesh,1 Paria Dehesh,2 Mohammad Hossein Gozashti31Department of Biostatistics and Epidemiology, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran; 2Graduated of Veterinary Medicine Faculty, Shahid Bahonar University of Kerman, Kerman, Iran; 3Department of Endocrinology, Kerman University of Medical Sciences, Kerman, IranPurpose: In the past few decades, an increase in the life span of the population has caused more people to experience chronic diseases, such as type 2 diabetes. Since chronic diseases influence the whole life of patients and do not have a specific remedy, improving their health-related quality of life (HRQoL) becomes more important. The aim of the present study was to investigate the metabolic variables that influenced HRQoL questionnaire scores most significantly among patients with type 2 diabetes.Patients and methods: The population of this cross-sectional study included 163 patients with type 2 diabetes and 214 healthy people who were asked to complete the HRQoL questionnaire, and their metabolic blood variables were recorded simultaneously. The effects of metabolic variables and some other demographic ones on two main scales of HRQoL, Mental Component Summary (MCS) and Physical Component Summary (PCS), were evaluated using multivariate regression.Results: Multivariate regression analysis showed that PCS score was most negatively influenced by cigarette smoking (P=0.009, β-15.761), maximum blood pressure (P=0.008, β=−0.108), minimum blood pressure (P=0.009, β=−0.039), low-density lipoprotein cholesterol (P=0.008, β=−0.721), cholesterol (P=0.006, β=−0.648), HbA1c (P=0.004, β=–0.878), FBS (p=0.006, β=−0.769), and body mass index (BMI) (P=0.034, β=–0.287). The MCS score was influenced positively by smoking cigarettes (P=0.041, β=13.032), gender (P=0.018, β=15.633), and BMI (P=0.048, β=−0.088). Men had a higher MCS score compared to women.Conclusion: The HRQoL questionnaire (as a concept of health) score could be improved by controlling the variation of some metabolic variables in patients with type 2 diabetes. Some metabolic variables could be the main causes of a decrease in physical and mental HRQoL among patients with type 2 diabetes.Keywords: quality of life, SF-36 questionnaire, metabolic variablesDehesh TDehesh PGozashti MHDove Medical PressarticleQuality of LifeSF-36 questionnairemetabolic variablesSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 12, Pp 1181-1188 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Quality of Life SF-36 questionnaire metabolic variables Specialties of internal medicine RC581-951
spellingShingle	Quality of Life SF-36 questionnaire metabolic variables Specialties of internal medicine RC581-951 Dehesh T Dehesh P Gozashti MH Metabolic factors that affect health-related quality of life in type 2 diabetes patients: a multivariate regression analysis
description	Tania Dehesh,1 Paria Dehesh,2 Mohammad Hossein Gozashti31Department of Biostatistics and Epidemiology, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran; 2Graduated of Veterinary Medicine Faculty, Shahid Bahonar University of Kerman, Kerman, Iran; 3Department of Endocrinology, Kerman University of Medical Sciences, Kerman, IranPurpose: In the past few decades, an increase in the life span of the population has caused more people to experience chronic diseases, such as type 2 diabetes. Since chronic diseases influence the whole life of patients and do not have a specific remedy, improving their health-related quality of life (HRQoL) becomes more important. The aim of the present study was to investigate the metabolic variables that influenced HRQoL questionnaire scores most significantly among patients with type 2 diabetes.Patients and methods: The population of this cross-sectional study included 163 patients with type 2 diabetes and 214 healthy people who were asked to complete the HRQoL questionnaire, and their metabolic blood variables were recorded simultaneously. The effects of metabolic variables and some other demographic ones on two main scales of HRQoL, Mental Component Summary (MCS) and Physical Component Summary (PCS), were evaluated using multivariate regression.Results: Multivariate regression analysis showed that PCS score was most negatively influenced by cigarette smoking (P=0.009, β-15.761), maximum blood pressure (P=0.008, β=−0.108), minimum blood pressure (P=0.009, β=−0.039), low-density lipoprotein cholesterol (P=0.008, β=−0.721), cholesterol (P=0.006, β=−0.648), HbA1c (P=0.004, β=–0.878), FBS (p=0.006, β=−0.769), and body mass index (BMI) (P=0.034, β=–0.287). The MCS score was influenced positively by smoking cigarettes (P=0.041, β=13.032), gender (P=0.018, β=15.633), and BMI (P=0.048, β=−0.088). Men had a higher MCS score compared to women.Conclusion: The HRQoL questionnaire (as a concept of health) score could be improved by controlling the variation of some metabolic variables in patients with type 2 diabetes. Some metabolic variables could be the main causes of a decrease in physical and mental HRQoL among patients with type 2 diabetes.Keywords: quality of life, SF-36 questionnaire, metabolic variables
format	article
author	Dehesh T Dehesh P Gozashti MH
author_facet	Dehesh T Dehesh P Gozashti MH
author_sort	Dehesh T
title	Metabolic factors that affect health-related quality of life in type 2 diabetes patients: a multivariate regression analysis
title_short	Metabolic factors that affect health-related quality of life in type 2 diabetes patients: a multivariate regression analysis
title_full	Metabolic factors that affect health-related quality of life in type 2 diabetes patients: a multivariate regression analysis
title_fullStr	Metabolic factors that affect health-related quality of life in type 2 diabetes patients: a multivariate regression analysis
title_full_unstemmed	Metabolic factors that affect health-related quality of life in type 2 diabetes patients: a multivariate regression analysis
title_sort	metabolic factors that affect health-related quality of life in type 2 diabetes patients: a multivariate regression analysis
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/4fd4d81c1c334ec0846444b545539a03
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Metabolic factors that affect health-related quality of life in type 2 diabetes patients: a multivariate regression analysis

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