Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite

Plasmodium knowlesi infects macaques and can cause malaria in humans. Here, Dankwa et al. show that the absence of a sialic-acid component on the surface of macaque red blood cells (RBCs) limits infection of human RBCs with P. knowlesi, but the parasite can adapt to invade human RBCs by using altern...

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Autores principales:	Selasi Dankwa, Caeul Lim, Amy K. Bei, Rays H. Y. Jiang, James R. Abshire, Saurabh D. Patel, Jonathan M. Goldberg, Yovany Moreno, Maya Kono, Jacquin C. Niles, Manoj T. Duraisingh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4fe26786f5d64c4f806c253055c90e4d
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spelling	oai:doaj.org-article:4fe26786f5d64c4f806c253055c90e4d2021-12-02T15:34:53ZAncient human sialic acid variant restricts an emerging zoonotic malaria parasite10.1038/ncomms111872041-1723https://doaj.org/article/4fe26786f5d64c4f806c253055c90e4d2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11187https://doaj.org/toc/2041-1723Plasmodium knowlesi infects macaques and can cause malaria in humans. Here, Dankwa et al. show that the absence of a sialic-acid component on the surface of macaque red blood cells (RBCs) limits infection of human RBCs with P. knowlesi, but the parasite can adapt to invade human RBCs by using alternative pathways.Selasi DankwaCaeul LimAmy K. BeiRays H. Y. JiangJames R. AbshireSaurabh D. PatelJonathan M. GoldbergYovany MorenoMaya KonoJacquin C. NilesManoj T. DuraisinghNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Selasi Dankwa Caeul Lim Amy K. Bei Rays H. Y. Jiang James R. Abshire Saurabh D. Patel Jonathan M. Goldberg Yovany Moreno Maya Kono Jacquin C. Niles Manoj T. Duraisingh Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite
description	Plasmodium knowlesi infects macaques and can cause malaria in humans. Here, Dankwa et al. show that the absence of a sialic-acid component on the surface of macaque red blood cells (RBCs) limits infection of human RBCs with P. knowlesi, but the parasite can adapt to invade human RBCs by using alternative pathways.
format	article
author	Selasi Dankwa Caeul Lim Amy K. Bei Rays H. Y. Jiang James R. Abshire Saurabh D. Patel Jonathan M. Goldberg Yovany Moreno Maya Kono Jacquin C. Niles Manoj T. Duraisingh
author_facet	Selasi Dankwa Caeul Lim Amy K. Bei Rays H. Y. Jiang James R. Abshire Saurabh D. Patel Jonathan M. Goldberg Yovany Moreno Maya Kono Jacquin C. Niles Manoj T. Duraisingh
author_sort	Selasi Dankwa
title	Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite
title_short	Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite
title_full	Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite
title_fullStr	Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite
title_full_unstemmed	Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite
title_sort	ancient human sialic acid variant restricts an emerging zoonotic malaria parasite
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/4fe26786f5d64c4f806c253055c90e4d
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Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite

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