Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite

Plasmodium knowlesi infects macaques and can cause malaria in humans. Here, Dankwa et al. show that the absence of a sialic-acid component on the surface of macaque red blood cells (RBCs) limits infection of human RBCs with P. knowlesi, but the parasite can adapt to invade human RBCs by using altern...

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Bibliographic Details
Main Authors: Selasi Dankwa, Caeul Lim, Amy K. Bei, Rays H. Y. Jiang, James R. Abshire, Saurabh D. Patel, Jonathan M. Goldberg, Yovany Moreno, Maya Kono, Jacquin C. Niles, Manoj T. Duraisingh
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/4fe26786f5d64c4f806c253055c90e4d
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