Single-Cell Transcriptomic Analysis Reveals a Tumor-Reactive T Cell Signature Associated With Clinical Outcome and Immunotherapy Response In Melanoma

The infiltration of tumor-reactive T cells in the tumor site is associated with better survival and immunotherapy response. However, tumor-reactive T cells were often represented by the infiltration of total CD8+ T cells, which was confounded by the presence of bystander T cells. To identify tumor-r...

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Bibliographic Details
Main Authors: Min Yan, Jing Hu, Yanyan Ping, Liwen Xu, Gaoming Liao, Zedong Jiang, Bo Pang, Shangqin Sun, Yunpeng Zhang, Yun Xiao, Xia Li
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/4ff13bfdd6ff4c63903dd4cd55fc2161
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