Single-Cell Transcriptomic Analysis Reveals a Tumor-Reactive T Cell Signature Associated With Clinical Outcome and Immunotherapy Response In Melanoma
The infiltration of tumor-reactive T cells in the tumor site is associated with better survival and immunotherapy response. However, tumor-reactive T cells were often represented by the infiltration of total CD8+ T cells, which was confounded by the presence of bystander T cells. To identify tumor-r...
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Main Authors: | , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Frontiers Media S.A.
2021
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Subjects: | |
Online Access: | https://doaj.org/article/4ff13bfdd6ff4c63903dd4cd55fc2161 |
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