Single-Cell Transcriptomic Analysis Reveals a Tumor-Reactive T Cell Signature Associated With Clinical Outcome and Immunotherapy Response In Melanoma
The infiltration of tumor-reactive T cells in the tumor site is associated with better survival and immunotherapy response. However, tumor-reactive T cells were often represented by the infiltration of total CD8+ T cells, which was confounded by the presence of bystander T cells. To identify tumor-r...
Guardado en:
Autores principales: | Min Yan, Jing Hu, Yanyan Ping, Liwen Xu, Gaoming Liao, Zedong Jiang, Bo Pang, Shangqin Sun, Yunpeng Zhang, Yun Xiao, Xia Li |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/4ff13bfdd6ff4c63903dd4cd55fc2161 |
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