Single-molecule theory of enzymatic inhibition

Single molecule approaches demonstrated that enzymatic catalysis is stochastic which could lead to deviations from classical predictions. Here authors rebuild the theory of enzymatic inhibition to show that stochastic fluctuations on the single enzyme level could make inhibitors act as activators.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tal Robin, Shlomi Reuveni, Michael Urbakh
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/4ff682a5b6ec47f9b1d180b0cef1fdf2
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!