Negligible colon cancer risk from food-borne acrylamide exposure in male F344 rats and nude (nu/nu) mice-bearing human colon tumor xenografts.
Acrylamide, a possible human carcinogen, is formed in certain carbohydrate-rich foods processed at high temperature. We evaluated if dietary acrylamide, at doses (0.5, 1.0 or 2.0 mg/kg diet) reflecting upper levels found in human foods, modulated colon tumorigenesis in two rodent models. Male F344 r...
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Main Authors: | Jayadev Raju, Jennifer Roberts, Chandni Sondagar, Kamla Kapal, Syed A Aziz, Don Caldwell, Rekha Mehta |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/500d7b8d07cd4e24b5555659e23d25d8 |
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