Interleukin-27 signaling promotes immunity against endogenously arising murine tumors.

Interleukin-27 (IL-27) is a pleiotropic cytokine but its immunosuppressive effects predominate during many in vivo immunological challenges. Despite this, evidence from tumor cell line transfer models suggested that IL-27 could promote immune responses in the tumor context. However, the role of IL-2...

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Autores principales: Karlo D T Natividad, Simon R Junankar, Norhanani Mohd Redzwan, Radhika Nair, Rushika C Wirasinha, Cecile King, Robert Brink, Alexander Swarbrick, Marcel Batten
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/5013b632422a4d79b8f418f45485d116
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