A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle

A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle

The female reproductive tract constitutes the ovary, fallopian tubes, uterus, and cervix, but it is challenging to engineer this systemin vitro. Here, the authors develop a microfluidic device (EVATAR) with reproductive tract and peripheral tissues to replicate hormone release of a 28-day menstrual...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Shuo Xiao, Jonathan R. Coppeta, Hunter B. Rogers, Brett C. Isenberg, Jie Zhu, Susan A. Olalekan, Kelly E. McKinnon, Danijela Dokic, Alexandra S. Rashedi, Daniel J. Haisenleder, Saurabh S. Malpani, Chanel A. Arnold-Murray, Kuanwei Chen, Mingyang Jiang, Lu Bai, Catherine T. Nguyen, Jiyang Zhang, Monica M. Laronda, Thomas J. Hope, Kruti P. Maniar, Mary Ellen Pavone, Michael J. Avram, Elizabeth C. Sefton, Spiro Getsios, Joanna E. Burdette, J. Julie Kim, Jeffrey T. Borenstein, Teresa K. Woodruff
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/502594c466a14109b2eb6d7e22593a42
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:502594c466a14109b2eb6d7e22593a42
record_format dspace
spelling oai:doaj.org-article:502594c466a14109b2eb6d7e22593a422021-12-02T14:41:18ZA microfluidic culture model of the human reproductive tract and 28-day menstrual cycle10.1038/ncomms145842041-1723https://doaj.org/article/502594c466a14109b2eb6d7e22593a422017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14584https://doaj.org/toc/2041-1723The female reproductive tract constitutes the ovary, fallopian tubes, uterus, and cervix, but it is challenging to engineer this systemin vitro. Here, the authors develop a microfluidic device (EVATAR) with reproductive tract and peripheral tissues to replicate hormone release of a 28-day menstrual cycle.Shuo XiaoJonathan R. CoppetaHunter B. RogersBrett C. IsenbergJie ZhuSusan A. OlalekanKelly E. McKinnonDanijela DokicAlexandra S. RashediDaniel J. HaisenlederSaurabh S. MalpaniChanel A. Arnold-MurrayKuanwei ChenMingyang JiangLu BaiCatherine T. NguyenJiyang ZhangMonica M. LarondaThomas J. HopeKruti P. ManiarMary Ellen PavoneMichael J. AvramElizabeth C. SeftonSpiro GetsiosJoanna E. BurdetteJ. Julie KimJeffrey T. BorensteinTeresa K. WoodruffNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shuo Xiao
Jonathan R. Coppeta
Hunter B. Rogers
Brett C. Isenberg
Jie Zhu
Susan A. Olalekan
Kelly E. McKinnon
Danijela Dokic
Alexandra S. Rashedi
Daniel J. Haisenleder
Saurabh S. Malpani
Chanel A. Arnold-Murray
Kuanwei Chen
Mingyang Jiang
Lu Bai
Catherine T. Nguyen
Jiyang Zhang
Monica M. Laronda
Thomas J. Hope
Kruti P. Maniar
Mary Ellen Pavone
Michael J. Avram
Elizabeth C. Sefton
Spiro Getsios
Joanna E. Burdette
J. Julie Kim
Jeffrey T. Borenstein
Teresa K. Woodruff
A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle
description The female reproductive tract constitutes the ovary, fallopian tubes, uterus, and cervix, but it is challenging to engineer this systemin vitro. Here, the authors develop a microfluidic device (EVATAR) with reproductive tract and peripheral tissues to replicate hormone release of a 28-day menstrual cycle.
format article
author Shuo Xiao
Jonathan R. Coppeta
Hunter B. Rogers
Brett C. Isenberg
Jie Zhu
Susan A. Olalekan
Kelly E. McKinnon
Danijela Dokic
Alexandra S. Rashedi
Daniel J. Haisenleder
Saurabh S. Malpani
Chanel A. Arnold-Murray
Kuanwei Chen
Mingyang Jiang
Lu Bai
Catherine T. Nguyen
Jiyang Zhang
Monica M. Laronda
Thomas J. Hope
Kruti P. Maniar
Mary Ellen Pavone
Michael J. Avram
Elizabeth C. Sefton
Spiro Getsios
Joanna E. Burdette
J. Julie Kim
Jeffrey T. Borenstein
Teresa K. Woodruff
author_facet Shuo Xiao
Jonathan R. Coppeta
Hunter B. Rogers
Brett C. Isenberg
Jie Zhu
Susan A. Olalekan
Kelly E. McKinnon
Danijela Dokic
Alexandra S. Rashedi
Daniel J. Haisenleder
Saurabh S. Malpani
Chanel A. Arnold-Murray
Kuanwei Chen
Mingyang Jiang
Lu Bai
Catherine T. Nguyen
Jiyang Zhang
Monica M. Laronda
Thomas J. Hope
Kruti P. Maniar
Mary Ellen Pavone
Michael J. Avram
Elizabeth C. Sefton
Spiro Getsios
Joanna E. Burdette
J. Julie Kim
Jeffrey T. Borenstein
Teresa K. Woodruff
author_sort Shuo Xiao
title A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle
title_short A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle
title_full A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle
title_fullStr A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle
title_full_unstemmed A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle
title_sort microfluidic culture model of the human reproductive tract and 28-day menstrual cycle
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/502594c466a14109b2eb6d7e22593a42
work_keys_str_mv AT shuoxiao amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT jonathanrcoppeta amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT hunterbrogers amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT brettcisenberg amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT jiezhu amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT susanaolalekan amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT kellyemckinnon amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT danijeladokic amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT alexandrasrashedi amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT danieljhaisenleder amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT saurabhsmalpani amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT chanelaarnoldmurray amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT kuanweichen amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT mingyangjiang amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT lubai amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT catherinetnguyen amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT jiyangzhang amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT monicamlaronda amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT thomasjhope amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT krutipmaniar amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT maryellenpavone amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT michaeljavram amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT elizabethcsefton amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT spirogetsios amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT joannaeburdette amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT jjuliekim amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT jeffreytborenstein amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT teresakwoodruff amicrofluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT shuoxiao microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT jonathanrcoppeta microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT hunterbrogers microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT brettcisenberg microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT jiezhu microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT susanaolalekan microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT kellyemckinnon microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT danijeladokic microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT alexandrasrashedi microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT danieljhaisenleder microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT saurabhsmalpani microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT chanelaarnoldmurray microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT kuanweichen microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT mingyangjiang microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT lubai microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT catherinetnguyen microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT jiyangzhang microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT monicamlaronda microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT thomasjhope microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT krutipmaniar microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT maryellenpavone microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT michaeljavram microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT elizabethcsefton microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT spirogetsios microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT joannaeburdette microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT jjuliekim microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT jeffreytborenstein microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
AT teresakwoodruff microfluidicculturemodelofthehumanreproductivetractand28daymenstrualcycle
_version_ 1718389929782804480

Ejemplares similares