Reader domain specificity and lysine demethylase-4 family function

KDM4 histone demethylases target specific chromatin regions by a mechanism that is not fully characterised. Here, the authors identify trimethyl-lysine histone-binding preferences for closely related KDM4 double tudor domains and use structural and biochemical information to examine the molecular de...

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Autores principales:	Zhangli Su, Fengbin Wang, Jin-Hee Lee, Kimberly E. Stephens, Romeo Papazyan, Ekaterina Voronina, Kimberly A. Krautkramer, Ana Raman, Jeremy J. Thorpe, Melissa D. Boersma, Vyacheslav I. Kuznetsov, Mitchell D. Miller, Sean D. Taverna, George N. Phillips, John M. Denu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/502865cd91ae47c58370ec2f6dd3787b
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spelling	oai:doaj.org-article:502865cd91ae47c58370ec2f6dd3787b2021-12-02T16:56:45ZReader domain specificity and lysine demethylase-4 family function10.1038/ncomms133872041-1723https://doaj.org/article/502865cd91ae47c58370ec2f6dd3787b2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13387https://doaj.org/toc/2041-1723KDM4 histone demethylases target specific chromatin regions by a mechanism that is not fully characterised. Here, the authors identify trimethyl-lysine histone-binding preferences for closely related KDM4 double tudor domains and use structural and biochemical information to examine the molecular details of this interaction.Zhangli SuFengbin WangJin-Hee LeeKimberly E. StephensRomeo PapazyanEkaterina VoroninaKimberly A. KrautkramerAna RamanJeremy J. ThorpeMelissa D. BoersmaVyacheslav I. KuznetsovMitchell D. MillerSean D. TavernaGeorge N. PhillipsJohn M. DenuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhangli Su Fengbin Wang Jin-Hee Lee Kimberly E. Stephens Romeo Papazyan Ekaterina Voronina Kimberly A. Krautkramer Ana Raman Jeremy J. Thorpe Melissa D. Boersma Vyacheslav I. Kuznetsov Mitchell D. Miller Sean D. Taverna George N. Phillips John M. Denu Reader domain specificity and lysine demethylase-4 family function
description	KDM4 histone demethylases target specific chromatin regions by a mechanism that is not fully characterised. Here, the authors identify trimethyl-lysine histone-binding preferences for closely related KDM4 double tudor domains and use structural and biochemical information to examine the molecular details of this interaction.
format	article
author	Zhangli Su Fengbin Wang Jin-Hee Lee Kimberly E. Stephens Romeo Papazyan Ekaterina Voronina Kimberly A. Krautkramer Ana Raman Jeremy J. Thorpe Melissa D. Boersma Vyacheslav I. Kuznetsov Mitchell D. Miller Sean D. Taverna George N. Phillips John M. Denu
author_facet	Zhangli Su Fengbin Wang Jin-Hee Lee Kimberly E. Stephens Romeo Papazyan Ekaterina Voronina Kimberly A. Krautkramer Ana Raman Jeremy J. Thorpe Melissa D. Boersma Vyacheslav I. Kuznetsov Mitchell D. Miller Sean D. Taverna George N. Phillips John M. Denu
author_sort	Zhangli Su
title	Reader domain specificity and lysine demethylase-4 family function
title_short	Reader domain specificity and lysine demethylase-4 family function
title_full	Reader domain specificity and lysine demethylase-4 family function
title_fullStr	Reader domain specificity and lysine demethylase-4 family function
title_full_unstemmed	Reader domain specificity and lysine demethylase-4 family function
title_sort	reader domain specificity and lysine demethylase-4 family function
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/502865cd91ae47c58370ec2f6dd3787b
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Reader domain specificity and lysine demethylase-4 family function

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