A role for ABCB1 in prognosis, invasion and drug resistance in ependymoma
Abstract Three of the hallmarks of poor prognosis in paediatric ependymoma are drug resistance, local invasion and recurrence. We hypothesised that these hallmarks were due to the presence of a sub-population of cancer stem cells expressing the multi-drug efflux transporter ABCB1. ABCB1 gene express...
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Autores principales: | Durgagauri H. Sabnis, Lisa C. D. Storer, Jo-Fen Liu, Hannah K. Jackson, J. P. Kilday, Richard G. Grundy, Ian D. Kerr, Beth Coyle |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/502c6a04b51647b3a5dd47133c1f5c73 |
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