BDNF produced by cerebral microglia promotes cortical plasticity and pain hypersensitivity after peripheral nerve injury.
Peripheral nerve injury-induced mechanical allodynia is often accompanied by abnormalities in the higher cortical regions, yet the mechanisms underlying such maladaptive cortical plasticity remain unclear. Here, we show that in male mice, structural and functional changes in the primary somatosensor...
Guardado en:
Autores principales: | Lianyan Huang, Jianhua Jin, Kai Chen, Sikun You, Hongyang Zhang, Alexandra Sideris, Monica Norcini, Esperanza Recio-Pinto, Jing Wang, Wen-Biao Gan, Guang Yang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5030bc8459b24a71915c2d3913f29852 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Author Correction: BDNF contributes to IBS-like colonic hypersensitivity via activating the enteroglia-nerve unit
por: Peng Wang, et al.
Publicado: (2021) -
Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia
por: Peter L. Wang, et al.
Publicado: (2020) -
Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice
por: Julia A Kuhn, et al.
Publicado: (2021) -
Microglia and monocytes synergistically promote the transition from acute to chronic pain after nerve injury
por: Jiyun Peng, et al.
Publicado: (2016) -
Posteroanterior Cervical Transcutaneous Spinal Cord Stimulation: Interactions with Cortical and Peripheral Nerve Stimulation
por: Jaclyn R. Wecht, et al.
Publicado: (2021)