The microprotein Minion controls cell fusion and muscle formation

Cellular fusion is essential for skeletal muscle development. Here the authors identify Minion as a microprotein required for myoblast fusion and skeletal muscle formation, and show that co-expression of Minion and Myomaker is sufficient to induce cytoskeletal rearrangement and cell fusion even in n...

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Autores principales:	Qiao Zhang, Ajay A. Vashisht, Jason O’Rourke, Stéphane Y Corbel, Rita Moran, Angelica Romero, Loren Miraglia, Jia Zhang, Eric Durrant, Christian Schmedt, Srinath C. Sampath, Srihari C. Sampath
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5037962f1d194b6898a8441181d864fd
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spelling	oai:doaj.org-article:5037962f1d194b6898a8441181d864fd2021-12-02T15:38:41ZThe microprotein Minion controls cell fusion and muscle formation10.1038/ncomms156642041-1723https://doaj.org/article/5037962f1d194b6898a8441181d864fd2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15664https://doaj.org/toc/2041-1723Cellular fusion is essential for skeletal muscle development. Here the authors identify Minion as a microprotein required for myoblast fusion and skeletal muscle formation, and show that co-expression of Minion and Myomaker is sufficient to induce cytoskeletal rearrangement and cell fusion even in non-muscle cells.Qiao ZhangAjay A. VashishtJason O’RourkeStéphane Y CorbelRita MoranAngelica RomeroLoren MiragliaJia ZhangEric DurrantChristian SchmedtSrinath C. SampathSrihari C. SampathNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qiao Zhang Ajay A. Vashisht Jason O’Rourke Stéphane Y Corbel Rita Moran Angelica Romero Loren Miraglia Jia Zhang Eric Durrant Christian Schmedt Srinath C. Sampath Srihari C. Sampath The microprotein Minion controls cell fusion and muscle formation
description	Cellular fusion is essential for skeletal muscle development. Here the authors identify Minion as a microprotein required for myoblast fusion and skeletal muscle formation, and show that co-expression of Minion and Myomaker is sufficient to induce cytoskeletal rearrangement and cell fusion even in non-muscle cells.
format	article
author	Qiao Zhang Ajay A. Vashisht Jason O’Rourke Stéphane Y Corbel Rita Moran Angelica Romero Loren Miraglia Jia Zhang Eric Durrant Christian Schmedt Srinath C. Sampath Srihari C. Sampath
author_facet	Qiao Zhang Ajay A. Vashisht Jason O’Rourke Stéphane Y Corbel Rita Moran Angelica Romero Loren Miraglia Jia Zhang Eric Durrant Christian Schmedt Srinath C. Sampath Srihari C. Sampath
author_sort	Qiao Zhang
title	The microprotein Minion controls cell fusion and muscle formation
title_short	The microprotein Minion controls cell fusion and muscle formation
title_full	The microprotein Minion controls cell fusion and muscle formation
title_fullStr	The microprotein Minion controls cell fusion and muscle formation
title_full_unstemmed	The microprotein Minion controls cell fusion and muscle formation
title_sort	microprotein minion controls cell fusion and muscle formation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/5037962f1d194b6898a8441181d864fd
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The microprotein Minion controls cell fusion and muscle formation

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