Specific and nondisruptive interaction of guanidium-functionalized gold nanoparticles with neutral phospholipid bilayers

Guanidinium-containing macromolecules, such as arginine-rich peptides, have peculiar properties in their interactions with membranes, including efficient translocation. Here the authors show that cationic gold nanoparticles functionalized with guanidinium groups can specifically and nondisruptively...

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Autores principales:	Lucía Morillas-Becerril, Sebastian Franco-Ulloa, Ilaria Fortunati, Roberto Marotta, Xiaohuan Sun, Giordano Zanoni, Marco De Vivo, Fabrizio Mancin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/5045bf3f29fc455584e389dcd93af023
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spelling	oai:doaj.org-article:5045bf3f29fc455584e389dcd93af0232021-12-02T17:23:24ZSpecific and nondisruptive interaction of guanidium-functionalized gold nanoparticles with neutral phospholipid bilayers10.1038/s42004-021-00526-x2399-3669https://doaj.org/article/5045bf3f29fc455584e389dcd93af0232021-06-01T00:00:00Zhttps://doi.org/10.1038/s42004-021-00526-xhttps://doaj.org/toc/2399-3669Guanidinium-containing macromolecules, such as arginine-rich peptides, have peculiar properties in their interactions with membranes, including efficient translocation. Here the authors show that cationic gold nanoparticles functionalized with guanidinium groups can specifically and nondisruptively interact with phospholipid bilayer membranes.Lucía Morillas-BecerrilSebastian Franco-UlloaIlaria FortunatiRoberto MarottaXiaohuan SunGiordano ZanoniMarco De VivoFabrizio MancinNature PortfolioarticleChemistryQD1-999ENCommunications Chemistry, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Chemistry QD1-999
spellingShingle	Chemistry QD1-999 Lucía Morillas-Becerril Sebastian Franco-Ulloa Ilaria Fortunati Roberto Marotta Xiaohuan Sun Giordano Zanoni Marco De Vivo Fabrizio Mancin Specific and nondisruptive interaction of guanidium-functionalized gold nanoparticles with neutral phospholipid bilayers
description	Guanidinium-containing macromolecules, such as arginine-rich peptides, have peculiar properties in their interactions with membranes, including efficient translocation. Here the authors show that cationic gold nanoparticles functionalized with guanidinium groups can specifically and nondisruptively interact with phospholipid bilayer membranes.
format	article
author	Lucía Morillas-Becerril Sebastian Franco-Ulloa Ilaria Fortunati Roberto Marotta Xiaohuan Sun Giordano Zanoni Marco De Vivo Fabrizio Mancin
author_facet	Lucía Morillas-Becerril Sebastian Franco-Ulloa Ilaria Fortunati Roberto Marotta Xiaohuan Sun Giordano Zanoni Marco De Vivo Fabrizio Mancin
author_sort	Lucía Morillas-Becerril
title	Specific and nondisruptive interaction of guanidium-functionalized gold nanoparticles with neutral phospholipid bilayers
title_short	Specific and nondisruptive interaction of guanidium-functionalized gold nanoparticles with neutral phospholipid bilayers
title_full	Specific and nondisruptive interaction of guanidium-functionalized gold nanoparticles with neutral phospholipid bilayers
title_fullStr	Specific and nondisruptive interaction of guanidium-functionalized gold nanoparticles with neutral phospholipid bilayers
title_full_unstemmed	Specific and nondisruptive interaction of guanidium-functionalized gold nanoparticles with neutral phospholipid bilayers
title_sort	specific and nondisruptive interaction of guanidium-functionalized gold nanoparticles with neutral phospholipid bilayers
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5045bf3f29fc455584e389dcd93af023
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Specific and nondisruptive interaction of guanidium-functionalized gold nanoparticles with neutral phospholipid bilayers

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