Postnatal DNA demethylation and its role in tissue maturation
Here the authors show that a large fraction of the tissue-specific methylation pattern is generated postnatally. These changes, which occur in response to hormone signaling, appear to play a major role in the regulation of gene expression and tissue maturation in the liver.
Guardado en:
Autores principales: | Yitzhak Reizel, Ofra Sabag, Yael Skversky, Adam Spiro, Benjamin Steinberg, Diana Bernstein, Amber Wang, Julia Kieckhaefer, Catherine Li, Eli Pikarsky, Rena Levin-Klein, Alon Goren, Klaus Rajewsky, Klaus H. Kaestner, Howard Cedar |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/50520c8d9e7d4a71beda66e83fbcd1e0 |
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