Postnatal DNA demethylation and its role in tissue maturation

Postnatal DNA demethylation and its role in tissue maturation

Here the authors show that a large fraction of the tissue-specific methylation pattern is generated postnatally. These changes, which occur in response to hormone signaling, appear to play a major role in the regulation of gene expression and tissue maturation in the liver.

Saved in:
Bibliographic Details
Main Authors: Yitzhak Reizel, Ofra Sabag, Yael Skversky, Adam Spiro, Benjamin Steinberg, Diana Bernstein, Amber Wang, Julia Kieckhaefer, Catherine Li, Eli Pikarsky, Rena Levin-Klein, Alon Goren, Klaus Rajewsky, Klaus H. Kaestner, Howard Cedar
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
Q
Online Access:https://doaj.org/article/50520c8d9e7d4a71beda66e83fbcd1e0
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/50520c8d9e7d4a71beda66e83fbcd1e0

Similar Items